Product Information
APRACLONIDINE HCL 0.5% DROPS is a generic product labeled by Sandoz Inc., priced at $9.4529 per ML under NDC 61314066505. Its NADAC has been published 652 times since Nov 28, 2013.
FDA first approved this application on Jul 30, 1993. Its Orange Book therapeutic-equivalence code is AT.
Strength
5.75 mg/mL
Manufacturer
Sandoz Inc.NDC
61314066505
Classification
Generic
Dosage Form
SOLUTION
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
APRACLONIDINE HYDROCHLORIDEApproval Type
Authorized Generic (NDA)
FDA Application
NDA020258FDA Approved
7/30/1993
TE Code
AT
On Market Since
7/19/2009
Pharmacological Classes
Price Statistics
The NADAC for APRACLONIDINE HCL 0.5% DROPS has been published 652 times since Nov 28, 2013, and over the history we have for it it has declined 23.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $9.4529 per ML |
|---|---|
| All-time high | $12.4112 (Dec 11, 2013) |
| All-time low | $6.4505 (Jan 22, 2025) |
| 52-week high | $11.0700 |
| 52-week low | $9.4529 |
| Median price | $11.3176 |
| Average price | $11.1161 |
| Largest weekly change | -26.2% (Nov 20, 2024) |
| Weeks tracked | 652 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of APRACLONIDINE HCL 0.5% DROPS?
The current National Average Drug Acquisition Cost (NADAC) for APRACLONIDINE HCL 0.5% DROPS, manufactured by Sandoz Inc., is $9.4529 per ML (NDC 61314066505), effective Aug 19, 2026.
How has the price of APRACLONIDINE HCL 0.5% DROPS changed over time?
Over the history we have for it, the NADAC for APRACLONIDINE HCL 0.5% DROPS has declined 23.8%. It has been tracked across 652 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for APRACLONIDINE HCL 0.5% DROPS?
Since Nov 28, 2013, the NADAC for APRACLONIDINE HCL 0.5% DROPS has ranged from a low of $6.4505 (Jan 22, 2025) to a high of $12.4112 (Dec 11, 2013), with a median of $11.3176 per ML.
Are there cheaper alternatives to APRACLONIDINE HCL 0.5% DROPS?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as APRACLONIDINE HCL 0.5% DROPS in a comparable dosage form, but none are currently priced below it.
Who manufactures APRACLONIDINE HCL 0.5% DROPS?
APRACLONIDINE HCL 0.5% DROPS (NDC 61314066505) is labeled by Sandoz Inc., and CMS classifies it as a generic product.