Product Information
APRACLONIDINE HCL 0.5% DROPS is a generic product labeled by Sandoz Inc., priced at $9.5122 per ML under NDC 61314066510. Its NADAC has been published 70 times since Apr 23, 2025.
FDA first approved this application on Jul 30, 1993. Its Orange Book therapeutic-equivalence code is AT.
Strength
5.75 mg/mL
Manufacturer
Sandoz Inc.NDC
61314066510
Classification
Generic
Dosage Form
SOLUTION
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
APRACLONIDINE HYDROCHLORIDEApproval Type
Authorized Generic (NDA)
FDA Application
NDA020258FDA Approved
7/30/1993
TE Code
AT
On Market Since
7/19/2009
Pharmacological Classes
Price Statistics
The NADAC for APRACLONIDINE HCL 0.5% DROPS has been published 70 times since Apr 23, 2025, and over the history we have for it it has risen 37.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $9.5122 per ML |
|---|---|
| All-time high | $9.8938 (Jun 10, 2026) |
| All-time low | $6.9210 (Apr 23, 2025) |
| 52-week high | $9.8938 |
| 52-week low | $6.9210 |
| Median price | $6.9210 |
| Average price | $7.4862 |
| Largest weekly change | +43.0% (May 20, 2026) |
| Weeks tracked | 70 |
| Tracking since | Apr 23, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of APRACLONIDINE HCL 0.5% DROPS?
The current National Average Drug Acquisition Cost (NADAC) for APRACLONIDINE HCL 0.5% DROPS, manufactured by Sandoz Inc., is $9.5122 per ML (NDC 61314066510), effective Aug 19, 2026.
How has the price of APRACLONIDINE HCL 0.5% DROPS changed over time?
Over the history we have for it, the NADAC for APRACLONIDINE HCL 0.5% DROPS has risen 37.4%. It has been tracked across 70 weekly CMS publications since Apr 23, 2025.
What are the highest and lowest recorded NADAC prices for APRACLONIDINE HCL 0.5% DROPS?
Since Apr 23, 2025, the NADAC for APRACLONIDINE HCL 0.5% DROPS has ranged from a low of $6.9210 (Apr 23, 2025) to a high of $9.8938 (Jun 10, 2026), with a median of $6.9210 per ML.
Are there cheaper alternatives to APRACLONIDINE HCL 0.5% DROPS?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, APRACLONIDINE HCL 0.5% DROPS, is $9.4529 per ML — about 1% below APRACLONIDINE HCL 0.5% DROPS.
Who manufactures APRACLONIDINE HCL 0.5% DROPS?
APRACLONIDINE HCL 0.5% DROPS (NDC 61314066510) is labeled by Sandoz Inc., and CMS classifies it as a generic product.