Product Information
APRACLONIDINE HCL 0.5% DROPS is a generic product labeled by Sandoz Inc., priced at $9.4220 per ML under NDC 61314066510. Its NADAC has been published 76 times since Apr 23, 2025.
FDA first approved this application on Jul 30, 1993. Its Orange Book therapeutic-equivalence code is AT.
Strength
5.75 mg/mL
Manufacturer
Sandoz Inc.NDC
61314066510
Classification
Generic
Dosage Form
SOLUTION
Route
OPHTHALMIC
Effective Date
9/23/2026
Active Ingredients
APRACLONIDINE HYDROCHLORIDEApproval Type
Authorized Generic (NDA)
FDA Application
NDA020258FDA Approved
7/30/1993
TE Code
AT
On Market Since
7/19/2009
Pharmacological Classes
Price Statistics
The NADAC for APRACLONIDINE HCL 0.5% DROPS has been published 76 times since Apr 23, 2025, and over the history we have for it it has risen 36.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $9.4220 per ML |
|---|---|
| All-time high | $9.8938 (Jun 10, 2026) |
| All-time low | $6.9210 (Apr 23, 2025) |
| 52-week high | $9.8938 |
| 52-week low | $6.9210 |
| Median price | $6.9210 |
| Average price | $7.6437 |
| Largest weekly change | +43.0% (May 20, 2026) |
| Weeks tracked | 76 |
| Tracking since | Apr 23, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Sandoz Inc. manufacturer profile
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Drug market
Apraclonidine market comparison
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Therapeutic class
alpha-Adrenergic Agonist class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of APRACLONIDINE HCL 0.5% DROPS?
The current National Average Drug Acquisition Cost (NADAC) for APRACLONIDINE HCL 0.5% DROPS, manufactured by Sandoz Inc., is $9.4220 per ML (NDC 61314066510), effective Sep 30, 2026.
How has the price of APRACLONIDINE HCL 0.5% DROPS changed over time?
Over the history we have for it, the NADAC for APRACLONIDINE HCL 0.5% DROPS has risen 36.1%. It has been tracked across 76 weekly CMS publications since Apr 23, 2025.
What are the highest and lowest recorded NADAC prices for APRACLONIDINE HCL 0.5% DROPS?
Since Apr 23, 2025, the NADAC for APRACLONIDINE HCL 0.5% DROPS has ranged from a low of $6.9210 (Apr 23, 2025) to a high of $9.8938 (Jun 10, 2026), with a median of $6.9210 per ML.
Are there cheaper alternatives to APRACLONIDINE HCL 0.5% DROPS?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, APRACLONIDINE HCL 0.5% DROPS, is $9.1561 per ML — about 3% below APRACLONIDINE HCL 0.5% DROPS.
Who manufactures APRACLONIDINE HCL 0.5% DROPS?
APRACLONIDINE HCL 0.5% DROPS (NDC 61314066510) is labeled by Sandoz Inc., and CMS classifies it as a generic product.