Product Information
DIPHENHYDRAMINE 50 MG/ML VIAL is a generic product labeled by Fresenius Kabi USA, LLC, priced at $0.9336 per ML under NDC 63323066416. Its NADAC has been published 392 times since Oct 24, 2018.
FDA first approved this application on May 28, 2002. Its Orange Book therapeutic-equivalence code is AP.
Strength
50 mg/mL
Manufacturer
Fresenius Kabi USA, LLCNDC
63323066416
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS
Effective Date
8/19/2026
Active Ingredients
DIPHENHYDRAMINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040466FDA Approved
5/28/2002
TE Code
AP
On Market Since
8/1/2002
Pharmacological Classes
Price Statistics
The NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has been published 392 times since Oct 24, 2018, and over the history we have for it it has risen 34.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.9336 per ML |
|---|---|
| All-time high | $1.4470 (Apr 14, 2021) |
| All-time low | $0.6933 (Oct 24, 2018) |
| 52-week high | $0.9459 |
| 52-week low | $0.8905 |
| Median price | $0.9296 |
| Average price | $0.9376 |
| Largest weekly change | +51.1% (May 20, 2020) |
| Weeks tracked | 392 |
| Tracking since | Oct 24, 2018 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DIPHENHYDRAMINE 50 MG/ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 50 MG/ML VIAL, manufactured by Fresenius Kabi USA, LLC, is $0.9336 per ML (NDC 63323066416), effective Aug 19, 2026.
How has the price of DIPHENHYDRAMINE 50 MG/ML VIAL changed over time?
Over the history we have for it, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has risen 34.7%. It has been tracked across 392 weekly CMS publications since Oct 24, 2018.
What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 50 MG/ML VIAL?
Since Oct 24, 2018, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has ranged from a low of $0.6933 (Oct 24, 2018) to a high of $1.4470 (Apr 14, 2021), with a median of $0.9296 per ML.
Are there cheaper alternatives to DIPHENHYDRAMINE 50 MG/ML VIAL?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as DIPHENHYDRAMINE 50 MG/ML VIAL in a comparable dosage form, but none are currently priced below it.
Who manufactures DIPHENHYDRAMINE 50 MG/ML VIAL?
DIPHENHYDRAMINE 50 MG/ML VIAL (NDC 63323066416) is labeled by Fresenius Kabi USA, LLC, and CMS classifies it as a generic product.