Product Information
DIPHENHYDRAMINE 50 MG/ML VIAL is a generic product labeled by Fresenius Kabi USA, LLC, priced at $0.9399 per ML under NDC 63323066416. Its NADAC has been published 384 times since Oct 24, 2018.
Strength
50 mg/mL
Manufacturer
Fresenius Kabi USA, LLCNDC
63323066416
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS
Last Updated
6/17/2026
Active Ingredients
DIPHENHYDRAMINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040466On Market Since
8/1/2002
Pharmacological Classes
Price Statistics
The NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has been published 384 times since Oct 24, 2018, and over the history we have for it it has risen 35.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.9399 per ML |
|---|---|
| All-time high | $1.4470 (Apr 14, 2021) |
| All-time low | $0.6933 (Oct 24, 2018) |
| 52-week high | $0.9459 |
| 52-week low | $0.8905 |
| Median price | $0.9276 |
| Average price | $0.9375 |
| Largest weekly change | +51.1% (May 20, 2020) |
| Weeks tracked | 384 |
| Tracking since | Oct 24, 2018 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of DIPHENHYDRAMINE 50 MG/ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 50 MG/ML VIAL, manufactured by Fresenius Kabi USA, LLC, is $0.9399 per ML (NDC 63323066416), effective Jun 24, 2026.
How has the price of DIPHENHYDRAMINE 50 MG/ML VIAL changed over time?
Over the history we have for it, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has risen 35.6%. It has been tracked across 384 weekly CMS publications since Oct 24, 2018.
What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 50 MG/ML VIAL?
Since Oct 24, 2018, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has ranged from a low of $0.6933 (Oct 24, 2018) to a high of $1.4470 (Apr 14, 2021), with a median of $0.9276 per ML.
Are there cheaper alternatives to DIPHENHYDRAMINE 50 MG/ML VIAL?
Yes. 3 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, SLEEP AID 50 MG/30 ML LIQUID, is $0.0097 per ML — about 99% below DIPHENHYDRAMINE 50 MG/ML VIAL.
Who manufactures DIPHENHYDRAMINE 50 MG/ML VIAL?
DIPHENHYDRAMINE 50 MG/ML VIAL (NDC 63323066416) is labeled by Fresenius Kabi USA, LLC, and CMS classifies it as a generic product.
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