Product Information

AMRIX ER 15 MG CAPSULE is a brand product labeled by Cephalon, LLC, priced at $66.2326 per EA under NDC 63459070060. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Feb 1, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the Cyclobenzaprine Hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

AMRIX ER 15 MG CAPSULE

Cyclobenzaprine Hydrochloride
$66.2326per EA
High Outlier

Strength

15 mg/1

Manufacturer

Cephalon, LLC

NDC

63459070060

Classification

Brand

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

1/1/2026

Approval Type

New Drug (NDA)

FDA Application

NDA021777

FDA Approved

2/1/2007

TE Code

AB

On Market Since

10/2/2007

Pharmacological Classes

Centrally-mediated Muscle Relaxation
Muscle Relaxant

Price Statistics

The NADAC for AMRIX ER 15 MG CAPSULE has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 242.4%. The table below summarizes its recorded NADAC range and movement.

Current price$66.2326 per EA
All-time high$66.2326 (Aug 19, 2026)
All-time low$19.3423 (Nov 28, 2013)
52-week high$66.2326
52-week low$60.5416
Median price$40.2926
Average price$41.1291
Largest weekly change+9.9% (Jan 8, 2014)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

0.0%

3M

0.0%

6M

0.0%

1Y

+9.4%

3Y

+30.9%

5Y

+50.3%

All

+242.4%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 98% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of AMRIX ER 15 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for AMRIX ER 15 MG CAPSULE, manufactured by Cephalon, LLC, is $66.2326 per EA (NDC 63459070060), effective Aug 19, 2026.

How has the price of AMRIX ER 15 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for AMRIX ER 15 MG CAPSULE has risen 242.4%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for AMRIX ER 15 MG CAPSULE?

Since Nov 28, 2013, the NADAC for AMRIX ER 15 MG CAPSULE has ranged from a low of $19.3423 (Nov 28, 2013) to a high of $66.2326 (Aug 19, 2026), with a median of $40.2926 per EA.

Are there cheaper alternatives to AMRIX ER 15 MG CAPSULE?

Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CYCLOBENZAPRINE ER 15 MG CAP, is $1.2200 per EA — about 98% below AMRIX ER 15 MG CAPSULE.

Who manufactures AMRIX ER 15 MG CAPSULE?

AMRIX ER 15 MG CAPSULE (NDC 63459070060) is labeled by Cephalon, LLC, and CMS classifies it as a brand product.