Drug Markets/Cyclobenzaprine Hydrochloride

Cyclobenzaprine Hydrochloride

86 NDCs across 18 manufacturers|84 Generic,2 Brand

Cyclobenzaprine Hydrochloride is used to treat muscle cramp, muscle rigidity, muscle spasticity, myositis, pain and spasm, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved before 1982, and the first generic was approved May 3, 1989. FDA's Orange Book lists 39 AB-rated (therapeutically equivalent) products for this ingredient.

Cyclobenzaprine Hydrochloride is available as 86 NDCs from 18 manufacturers (84 generic, 2 brand), with NADAC prices from $0.02 to $66.57 per EA — the most expensive product costs about 3,888× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

84G / 2B

Manufacturers

competing in market

Price Spread

$0.02 – $66.57

per EA

7d Activity

69↑3↓14 flat

avg +3.0% WoW · of 86 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Explore this market from other angles

Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.

Top supplier

Rising Pharma Holdings Inc. manufacturer profile

Open the supplier page for the manufacturer with the strongest footprint in this market.

Lead class

Muscle Relaxant class view

See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.

Trend hub

Latest market trends

Move from this single molecule into the current cross-market mover and volatility view.

Guide

How to interpret NADAC

Review the benchmark methodology behind the prices and spreads shown on this market page.

Manufacturer Breakdown

18 manufacturers producing CYCLOBENZAPRINE HYDROCHLORIDE(4 pricing outliers)

Rising Pharma Holdings Inc.

13 NDCs

$0.0383

avg/unit

Teva Pharmaceuticals USA Inc.

Unichem Pharmaceuticals (USA) Inc.

Amneal Pharmaceuticals of New York LLC

Jubilant Cadista Pharmaceuticals Inc.

5 NDCs

$0.0682

avg/unit

Solco Healthcare US LLC

5 NDCs

$0.0191

avg/unit

Aurobindo Pharma Limited

4 NDCs

$0.0265

avg/unit

Amneal Pharmaceuticals LLC

3 NDCs

$0.0254

avg/unit

Major Pharmaceuticals

Upsher-Smith Laboratories LLC

American Health Packaging

SOLA Pharmaceuticals LLC

1 NDC

$0.0171

avg/unit

Drug Portfolio

86 NDCs total, 86 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
AMRIX ER 30 MG CAPSULE	63459070160	Cephalon, LLC	$66.5671 per EA	High Outlier	Brand	—	Muscle Relaxant
AMRIX ER 15 MG CAPSULE	63459070060	Cephalon, LLC	$66.2326 per EA	High Outlier	Brand	—	Muscle Relaxant
CYCLOBENZAPRINE ER 15 MG CAP	00093192006	Teva Pharmaceuticals USA Inc.	$1.1856 per EA	High Outlier	Generic	-2.82%	Muscle Relaxant
CYCLOBENZAPRINE ER 15 MG CAP	24979003504	Upsher-Smith Laboratories LLC	$1.1856 per EA	High Outlier	Generic	-2.82%	Muscle Relaxant
CYCLOBENZAPRINE ER 15 MG CAP	00115143613	Amneal Pharmaceuticals of New York LLC	$1.1856 per EA	High Outlier	Generic	-2.82%	Muscle Relaxant
CYCLOBENZAPRINE ER 30 MG CAP	24979003604	Upsher-Smith Laboratories LLC	$1.0822 per EA	High Outlier	Generic	+21.24%	Muscle Relaxant
CYCLOBENZAPRINE ER 30 MG CAP	00093192106	Teva Pharmaceuticals USA Inc.	$1.0822 per EA	High Outlier	Generic	+21.24%	Muscle Relaxant
CYCLOBENZAPRINE ER 30 MG CAP	00115143713	Amneal Pharmaceuticals of New York LLC	$1.0822 per EA	High Outlier	Generic	+21.24%	Muscle Relaxant
CYCLOBENZAPRINE 7.5 MG TABLET	52817033110	TruPharma LLC	$0.3553 per EA	—	Generic	—	Muscle Relaxant
CYCLOBENZAPRINE 7.5 MG TABLET	72888001301	Advagen Pharma Ltd.	$0.2629 per EA	—	Generic	+9.42%	Muscle Relaxant
CYCLOBENZAPRINE 7.5 MG TABLET	72603031101	NorthStar Rx LLC	$0.2629 per EA	—	Generic	+9.42%	Muscle Relaxant
FEXMID 7.5 MG TABLET	64980070501	Rising Pharma Holdings Inc.	$0.2629 per EA	—	Generic	+9.42%	Muscle Relaxant
CYCLOBENZAPRINE 7.5 MG TABLET	00093342101	Teva Pharmaceuticals USA Inc.	$0.2629 per EA	High Outlier	Generic	+9.42%	Muscle Relaxant
CYCLOBENZAPRINE 7.5 MG TABLET	59746073501	Jubilant Cadista Pharmaceuticals Inc.	$0.2629 per EA	—	Generic	+9.42%	Muscle Relaxant
CYCLOBENZAPRINE 7.5 MG TABLET	29300041401	Unichem Pharmaceuticals (USA) Inc.	$0.2629 per EA	—	Generic	+9.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	65862019001	Aurobindo Pharma Limited	$0.0410 per EA	—	Generic	—	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	53746054105	Amneal Pharmaceuticals of New York LLC	$0.0255 per EA	High Outlier	Generic	—	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	53746054101	Amneal Pharmaceuticals of New York LLC	$0.0255 per EA	High Outlier	Generic	—	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	53746054110	Amneal Pharmaceuticals of New York LLC	$0.0255 per EA	High Outlier	Generic	—	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	65162054150	Amneal Pharmaceuticals LLC	$0.0254 per EA	—	Generic	—	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	65162054110	Amneal Pharmaceuticals LLC	$0.0254 per EA	—	Generic	—	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	65162054111	Amneal Pharmaceuticals LLC	$0.0254 per EA	—	Generic	—	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	65862019199	Aurobindo Pharma Limited	$0.0245 per EA	—	Generic	—	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	65862019101	Aurobindo Pharma Limited	$0.0234 per EA	—	Generic	—	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	00904740006	Major Pharmaceuticals	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	00093342001	Teva Pharmaceuticals USA Inc.	$0.0220 per EA	High Outlier	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	00904740004	Major Pharmaceuticals	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	10702000601	KVK-Tech Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	10702000610	KVK-Tech Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	10702000650	KVK-Tech Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	16571078201	Rising Pharma Holdings Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	16571078210	Rising Pharma Holdings Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	16571078250	Rising Pharma Holdings Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	29300041301	Unichem Pharmaceuticals (USA) Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	29300041305	Unichem Pharmaceuticals (USA) Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	29300041319	Unichem Pharmaceuticals (USA) Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	43547039910	Solco Healthcare US LLC	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	43547039950	Solco Healthcare US LLC	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	50268019015	AvPAK	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	52817033010	TruPharma LLC	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	52817033050	TruPharma LLC	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	59746021106	Jubilant Cadista Pharmaceuticals Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	59746021110	Jubilant Cadista Pharmaceuticals Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	64980065501	Rising Pharma Holdings Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	64980065510	Rising Pharma Holdings Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	64980065550	Rising Pharma Holdings Inc.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	68084075325	American Health Packaging	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	68084075365	American Health Packaging	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	72603031001	NorthStar Rx LLC	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	72603031002	NorthStar Rx LLC	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	72888001200	Advagen Pharma Ltd.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	72888001201	Advagen Pharma Ltd.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 5 MG TABLET	72888001205	Advagen Pharma Ltd.	$0.0220 per EA	—	Generic	+2.42%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	10702000701	KVK-Tech Inc.	$0.0181 per EA	—	Generic	—	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	10702000709	KVK-Tech Inc.	$0.0181 per EA	—	Generic	—	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	65862019105	Aurobindo Pharma Limited	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	10702000750	KVK-Tech Inc.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	10702000710	KVK-Tech Inc.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	70512087210	SOLA Pharmaceuticals LLC	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	00904740161	Major Pharmaceuticals	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	43547040011	Solco Healthcare US LLC	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	72603031201	NorthStar Rx LLC	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	72603031202	NorthStar Rx LLC	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	72603031203	NorthStar Rx LLC	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	00093342210	Teva Pharmaceuticals USA Inc.	$0.0171 per EA	High Outlier	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	00093342205	Teva Pharmaceuticals USA Inc.	$0.0171 per EA	High Outlier	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	00093342201	Teva Pharmaceuticals USA Inc.	$0.0171 per EA	High Outlier	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	43547040010	Solco Healthcare US LLC	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	72888001400	Advagen Pharma Ltd.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	72888001401	Advagen Pharma Ltd.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	72888001405	Advagen Pharma Ltd.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	29300041519	Unichem Pharmaceuticals (USA) Inc.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	29300041510	Unichem Pharmaceuticals (USA) Inc.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	52817033210	TruPharma LLC	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	52817033250	TruPharma LLC	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	59746017706	Jubilant Cadista Pharmaceuticals Inc.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	59746017710	Jubilant Cadista Pharmaceuticals Inc.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	29300041501	Unichem Pharmaceuticals (USA) Inc.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	52817033200	TruPharma LLC	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	16571078350	Rising Pharma Holdings Inc.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	16571078310	Rising Pharma Holdings Inc.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	16571078301	Rising Pharma Holdings Inc.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	64980065701	Rising Pharma Holdings Inc.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	64980065750	Rising Pharma Holdings Inc.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	64980065710	Rising Pharma Holdings Inc.	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant
CYCLOBENZAPRINE 10 MG TABLET	43547040050	Solco Healthcare US LLC	$0.0171 per EA	—	Generic	+1.00%	Muscle Relaxant

Frequently Asked Questions

What is Cyclobenzaprine Hydrochloride used to treat?

Cyclobenzaprine Hydrochloride is used to treat muscle cramp, muscle rigidity, muscle spasticity, myositis, pain and spasm, per the National Library of Medicine's MED-RT classification.

When did Cyclobenzaprine Hydrochloride become available as a generic?

FDA approved the first generic Cyclobenzaprine Hydrochloride (ANDA) on May 3, 1989. The Orange Book currently lists 39 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How many Cyclobenzaprine Hydrochloride products are on the market?

The Cyclobenzaprine Hydrochloride drug market contains 86 NDCs from 18 manufacturers — 84 generic and 2 brand products.

What is the price range for Cyclobenzaprine Hydrochloride?

NADAC reference prices for Cyclobenzaprine Hydrochloride range from $0.0171 to $66.5671 per EA — the most expensive product costs about 3,888× the cheapest.

Is generic Cyclobenzaprine Hydrochloride cheaper than brand?

The average generic NADAC for Cyclobenzaprine Hydrochloride is $0.1212 per EA, versus $66.3998 for brand-labeled products — brand versions average about 548× the generic price.

Which manufacturers make Cyclobenzaprine Hydrochloride?

18 manufacturers list Cyclobenzaprine Hydrochloride in NADAC. Ranked by number of NDCs, the largest are Rising Pharma Holdings Inc. (13), Teva Pharmaceuticals USA Inc. (7), Advagen Pharma Ltd. (7), Unichem Pharmaceuticals (USA) Inc. (7), KVK-Tech Inc. (7).

How has the price of Cyclobenzaprine Hydrochloride changed recently?

Over the past 7 days, 69 Cyclobenzaprine Hydrochloride NDCs rose and 3 fell, with a market-wide average change of +3.0%.