Product Information
ISOSORBIDE DINITRATE 10 MG TAB is a generic product labeled by McKesson, priced at $0.1751 per EA under NDC 63739056910. Its NADAC has been published 526 times since Feb 3, 2016.
FDA first approved this application on Mar 12, 1987. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
10 mg/1
Manufacturer
McKessonNDC
63739056910
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
2/18/2026
Active Ingredients
ISOSORBIDE DINITRATEApproval Type
Generic (ANDA)
FDA Application
ANDA086925FDA Approved
3/12/1987
TE Code
AB
On Market Since
12/22/1979
Pharmacological Classes
Price Statistics
The NADAC for ISOSORBIDE DINITRATE 10 MG TAB has been published 526 times since Feb 3, 2016, and over the history we have for it it has declined 74.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1751 per EA |
|---|---|
| All-time high | $0.6908 (Feb 10, 2016) |
| All-time low | $0.1751 (Feb 18, 2026) |
| 52-week high | $0.2043 |
| 52-week low | $0.1751 |
| Median price | $0.3679 |
| Average price | $0.3943 |
| Largest weekly change | -19.9% (Sep 18, 2024) |
| Weeks tracked | 526 |
| Tracking since | Feb 3, 2016 |
1W
N/A
1M
N/A
3M
N/A
6M
0.0%
1Y
-12.4%
3Y
-39.9%
5Y
-52.2%
All
-74.7%
Last surveyed Feb 25, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 9% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ISOSORBIDE DINITRATE 10 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for ISOSORBIDE DINITRATE 10 MG TAB, manufactured by McKesson, is $0.1751 per EA (NDC 63739056910), effective Feb 25, 2026.
How has the price of ISOSORBIDE DINITRATE 10 MG TAB changed over time?
Over the history we have for it, the NADAC for ISOSORBIDE DINITRATE 10 MG TAB has declined 74.7%. It has been tracked across 526 weekly CMS publications since Feb 3, 2016.
What are the highest and lowest recorded NADAC prices for ISOSORBIDE DINITRATE 10 MG TAB?
Since Feb 3, 2016, the NADAC for ISOSORBIDE DINITRATE 10 MG TAB has ranged from a low of $0.1751 (Feb 18, 2026) to a high of $0.6908 (Feb 10, 2016), with a median of $0.3679 per EA.
Are there cheaper alternatives to ISOSORBIDE DINITRATE 10 MG TAB?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ISOSORBIDE DINITRATE 10 MG TAB, is $0.1596 per EA — about 9% below ISOSORBIDE DINITRATE 10 MG TAB.
Who manufactures ISOSORBIDE DINITRATE 10 MG TAB?
ISOSORBIDE DINITRATE 10 MG TAB (NDC 63739056910) is labeled by McKesson, and CMS classifies it as a generic product.