Product Information

PROPAFENONE HCL 300 MG TAB is a generic product labeled by Strides Pharma Inc., priced at $0.4247 per EA under NDC 64380016301. Its NADAC has been published 208 times since Aug 31, 2022.

FDA first approved this application on Oct 17, 2002. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

PROPAFENONE HCL 300 MG TAB

PROPAFENONE HYDROCHLORIDE
$0.4247per EA

Strength

300 mg/1

NDC

64380016301

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

PROPAFENONE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA075938

FDA Approved

10/17/2002

TE Code

AB

On Market Since

8/1/2022

Pharmacological Classes

Price Statistics

The NADAC for PROPAFENONE HCL 300 MG TAB has been published 208 times since Aug 31, 2022, and over the history we have for it it has declined 21.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.4247 per EA
All-time high$0.5873 (Mar 13, 2024)
All-time low$0.2331 (Nov 20, 2024)
52-week high$0.5292
52-week low$0.3530
Median price$0.4238
Average price$0.4193
Largest weekly change-42.9% (Mar 20, 2024)
Weeks tracked208
Tracking sinceAug 31, 2022

Price History

1W

-8.4%

1M

-8.4%

3M

-3.7%

6M

+2.2%

1Y

+20.3%

3Y

-21.5%

5Y

N/A

All

-21.5%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PROPAFENONE HCL 300 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for PROPAFENONE HCL 300 MG TAB, manufactured by Strides Pharma Inc., is $0.4247 per EA (NDC 64380016301), effective Aug 19, 2026.

How has the price of PROPAFENONE HCL 300 MG TAB changed over time?

Over the history we have for it, the NADAC for PROPAFENONE HCL 300 MG TAB has declined 21.5%. It has been tracked across 208 weekly CMS publications since Aug 31, 2022.

What are the highest and lowest recorded NADAC prices for PROPAFENONE HCL 300 MG TAB?

Since Aug 31, 2022, the NADAC for PROPAFENONE HCL 300 MG TAB has ranged from a low of $0.2331 (Nov 20, 2024) to a high of $0.5873 (Mar 13, 2024), with a median of $0.4238 per EA.

Are there cheaper alternatives to PROPAFENONE HCL 300 MG TAB?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROPAFENONE HCL 300 MG TAB in a comparable dosage form, but none are currently priced below it.

Who manufactures PROPAFENONE HCL 300 MG TAB?

PROPAFENONE HCL 300 MG TAB (NDC 64380016301) is labeled by Strides Pharma Inc., and CMS classifies it as a generic product.