Product Information
PROPAFENONE HCL 300 MG TAB is a generic product labeled by Strides Pharma Inc., priced at $0.3880 per EA under NDC 64380024601. Its NADAC has been published 66 times since Jul 2, 2025.
FDA first approved this application on Oct 17, 2002. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
300 mg/1
Manufacturer
Strides Pharma Inc.NDC
64380024601
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
PROPAFENONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA075938FDA Approved
10/17/2002
TE Code
AB
On Market Since
5/5/2025
Pharmacological Classes
Price Statistics
The NADAC for PROPAFENONE HCL 300 MG TAB has been published 66 times since Jul 2, 2025, and over the history we have for it it has risen 25.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3880 per EA |
|---|---|
| All-time high | $0.5292 (Dec 10, 2025) |
| All-time low | $0.3091 (Jul 2, 2025) |
| 52-week high | $0.5292 |
| 52-week low | $0.3880 |
| Median price | $0.4290 |
| Average price | $0.4291 |
| Largest weekly change | +21.5% (Sep 17, 2025) |
| Weeks tracked | 66 |
| Tracking since | Jul 2, 2025 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Strides Pharma Inc. manufacturer profile
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Drug market
PROPAFENONE HYDROCHLORIDE market comparison
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Therapeutic class
Antiarrhythmic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of PROPAFENONE HCL 300 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for PROPAFENONE HCL 300 MG TAB, manufactured by Strides Pharma Inc., is $0.3880 per EA (NDC 64380024601), effective Sep 30, 2026.
How has the price of PROPAFENONE HCL 300 MG TAB changed over time?
Over the history we have for it, the NADAC for PROPAFENONE HCL 300 MG TAB has risen 25.5%. It has been tracked across 66 weekly CMS publications since Jul 2, 2025.
What are the highest and lowest recorded NADAC prices for PROPAFENONE HCL 300 MG TAB?
Since Jul 2, 2025, the NADAC for PROPAFENONE HCL 300 MG TAB has ranged from a low of $0.3091 (Jul 2, 2025) to a high of $0.5292 (Dec 10, 2025), with a median of $0.4290 per EA.
Are there cheaper alternatives to PROPAFENONE HCL 300 MG TAB?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROPAFENONE HCL 300 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures PROPAFENONE HCL 300 MG TAB?
PROPAFENONE HCL 300 MG TAB (NDC 64380024601) is labeled by Strides Pharma Inc., and CMS classifies it as a generic product.