Product Information

PROPAFENONE HCL ER 325 MG CAP is a generic product labeled by Strides Pharma Inc., priced at $0.5300 per EA under NDC 64380018502. Its NADAC has been published 221 times since Jun 1, 2022.

FDA first approved this application on Oct 18, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

PROPAFENONE HCL ER 325 MG CAP

propafenone hydrochloride
$0.5300per EA

Strength

325 mg/1

NDC

64380018502

Classification

Generic

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

PROPAFENONE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA078540

FDA Approved

10/18/2010

TE Code

AB

On Market Since

4/4/2022

Pharmacological Classes

Price Statistics

The NADAC for PROPAFENONE HCL ER 325 MG CAP has been published 221 times since Jun 1, 2022, and over the history we have for it it has declined 51.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.5300 per EA
All-time high$1.5134 (Nov 15, 2023)
All-time low$0.4264 (Feb 18, 2026)
52-week high$0.7614
52-week low$0.4264
Median price$0.8829
Average price$0.9085
Largest weekly change+84.4% (Mar 20, 2024)
Weeks tracked221
Tracking sinceJun 1, 2022

Price History

1W

+7.7%

1M

+7.7%

3M

+13.7%

6M

+24.3%

1Y

-30.4%

3Y

-54.6%

5Y

N/A

All

-51.7%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PROPAFENONE HCL ER 325 MG CAP?

The current National Average Drug Acquisition Cost (NADAC) for PROPAFENONE HCL ER 325 MG CAP, manufactured by Strides Pharma Inc., is $0.5300 per EA (NDC 64380018502), effective Aug 19, 2026.

How has the price of PROPAFENONE HCL ER 325 MG CAP changed over time?

Over the history we have for it, the NADAC for PROPAFENONE HCL ER 325 MG CAP has declined 51.7%. It has been tracked across 221 weekly CMS publications since Jun 1, 2022.

What are the highest and lowest recorded NADAC prices for PROPAFENONE HCL ER 325 MG CAP?

Since Jun 1, 2022, the NADAC for PROPAFENONE HCL ER 325 MG CAP has ranged from a low of $0.4264 (Feb 18, 2026) to a high of $1.5134 (Nov 15, 2023), with a median of $0.8829 per EA.

Are there cheaper alternatives to PROPAFENONE HCL ER 325 MG CAP?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROPAFENONE HCL ER 325 MG CAP in a comparable dosage form, but none are currently priced below it.

Who manufactures PROPAFENONE HCL ER 325 MG CAP?

PROPAFENONE HCL ER 325 MG CAP (NDC 64380018502) is labeled by Strides Pharma Inc., and CMS classifies it as a generic product.