Product Information
PHENYLEPHRINE 2.5% EYE DROP is a generic product labeled by Caplin Steriles Limited, priced at $9.2005 per ML under NDC 65145014801. Its NADAC has been published 67 times since May 14, 2025.
FDA first approved this application on May 23, 2024. Its Orange Book therapeutic-equivalence code is AT.
Strength
25 mg/mL
Manufacturer
Caplin Steriles LimitedNDC
65145014801
Classification
Generic
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
PHENYLEPHRINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA215183FDA Approved
5/23/2024
TE Code
AT
On Market Since
1/23/2025
Pharmacological Classes
Price Statistics
The NADAC for PHENYLEPHRINE 2.5% EYE DROP has been published 67 times since May 14, 2025, and over the history we have for it it has declined 29.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $9.2005 per ML |
|---|---|
| All-time high | $12.9497 (May 14, 2025) |
| All-time low | $8.5534 (Feb 18, 2026) |
| 52-week high | $12.7786 |
| 52-week low | $8.5534 |
| Median price | $9.2765 |
| Average price | $10.4366 |
| Largest weekly change | -12.0% (Nov 19, 2025) |
| Weeks tracked | 67 |
| Tracking since | May 14, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 88% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PHENYLEPHRINE 2.5% EYE DROP?
The current National Average Drug Acquisition Cost (NADAC) for PHENYLEPHRINE 2.5% EYE DROP, manufactured by Caplin Steriles Limited, is $9.2005 per ML (NDC 65145014801), effective Aug 19, 2026.
How has the price of PHENYLEPHRINE 2.5% EYE DROP changed over time?
Over the history we have for it, the NADAC for PHENYLEPHRINE 2.5% EYE DROP has declined 29.0%. It has been tracked across 67 weekly CMS publications since May 14, 2025.
What are the highest and lowest recorded NADAC prices for PHENYLEPHRINE 2.5% EYE DROP?
Since May 14, 2025, the NADAC for PHENYLEPHRINE 2.5% EYE DROP has ranged from a low of $8.5534 (Feb 18, 2026) to a high of $12.9497 (May 14, 2025), with a median of $9.2765 per ML.
Are there cheaper alternatives to PHENYLEPHRINE 2.5% EYE DROP?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, PHENYLEPHRINE 2.5% EYE DROP, is $1.0784 per ML — about 88% below PHENYLEPHRINE 2.5% EYE DROP.
Who manufactures PHENYLEPHRINE 2.5% EYE DROP?
PHENYLEPHRINE 2.5% EYE DROP (NDC 65145014801) is labeled by Caplin Steriles Limited, and CMS classifies it as a generic product.