Product Information
PHENYLEPHRINE 2.5% EYE DROP is a generic product labeled by Caplin Steriles Limited, priced at $9.2924 per ML under NDC 65145014801. Its NADAC has been published 73 times since May 14, 2025.
FDA first approved this application on May 23, 2024. Its Orange Book therapeutic-equivalence code is AT.
Strength
25 mg/mL
Manufacturer
Caplin Steriles LimitedNDC
65145014801
Classification
Generic
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Effective Date
9/23/2026
Active Ingredients
PHENYLEPHRINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA215183FDA Approved
5/23/2024
TE Code
AT
On Market Since
1/23/2025
Pharmacological Classes
Price Statistics
The NADAC for PHENYLEPHRINE 2.5% EYE DROP has been published 73 times since May 14, 2025, and over the history we have for it it has declined 28.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $9.2924 per ML |
|---|---|
| All-time high | $12.9497 (May 14, 2025) |
| All-time low | $8.5534 (Feb 18, 2026) |
| 52-week high | $12.2873 |
| 52-week low | $8.5534 |
| Median price | $9.2765 |
| Average price | $10.3375 |
| Largest weekly change | -12.0% (Nov 19, 2025) |
| Weeks tracked | 73 |
| Tracking since | May 14, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 88% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Caplin Steriles Limited manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
phenylephrine hydrochloride market comparison
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Therapeutic class
alpha-1 Adrenergic Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of PHENYLEPHRINE 2.5% EYE DROP?
The current National Average Drug Acquisition Cost (NADAC) for PHENYLEPHRINE 2.5% EYE DROP, manufactured by Caplin Steriles Limited, is $9.2924 per ML (NDC 65145014801), effective Sep 30, 2026.
How has the price of PHENYLEPHRINE 2.5% EYE DROP changed over time?
Over the history we have for it, the NADAC for PHENYLEPHRINE 2.5% EYE DROP has declined 28.2%. It has been tracked across 73 weekly CMS publications since May 14, 2025.
What are the highest and lowest recorded NADAC prices for PHENYLEPHRINE 2.5% EYE DROP?
Since May 14, 2025, the NADAC for PHENYLEPHRINE 2.5% EYE DROP has ranged from a low of $8.5534 (Feb 18, 2026) to a high of $12.9497 (May 14, 2025), with a median of $9.2765 per ML.
Are there cheaper alternatives to PHENYLEPHRINE 2.5% EYE DROP?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, PHENYLEPHRINE 2.5% EYE DROP, is $1.0784 per ML — about 88% below PHENYLEPHRINE 2.5% EYE DROP.
Who manufactures PHENYLEPHRINE 2.5% EYE DROP?
PHENYLEPHRINE 2.5% EYE DROP (NDC 65145014801) is labeled by Caplin Steriles Limited, and CMS classifies it as a generic product.