Product Information
LYLLANA 0.025 MG PATCH is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $7.7586 per EA under NDC 65162012608. Its NADAC has been published 282 times since Feb 3, 2021.
Strength
.025 mg/d
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162012608
Classification
Generic
Dosage Form
PATCH, EXTENDED RELEASE
Route
TRANSDERMAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA211396On Market Since
9/30/2020
Pharmacological Classes
Price Statistics
The NADAC for LYLLANA 0.025 MG PATCH has been published 282 times since Feb 3, 2021, and over the history we have for it it has risen 10.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.7586 per EA |
|---|---|
| All-time high | $10.9520 (Jan 12, 2022) |
| All-time low | $4.9692 (Nov 20, 2024) |
| 52-week high | $7.7586 |
| 52-week low | $6.2985 |
| Median price | $6.7114 |
| Average price | $6.9780 |
| Largest weekly change | +47.0% (Dec 22, 2021) |
| Weeks tracked | 282 |
| Tracking since | Feb 3, 2021 |
Generic Alternatives
The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of LYLLANA 0.025 MG PATCH?
The current National Average Drug Acquisition Cost (NADAC) for LYLLANA 0.025 MG PATCH, manufactured by Amneal Pharmaceuticals LLC, is $7.7586 per EA (NDC 65162012608), effective Jun 24, 2026.
How has the price of LYLLANA 0.025 MG PATCH changed over time?
Over the history we have for it, the NADAC for LYLLANA 0.025 MG PATCH has risen 10.4%. It has been tracked across 282 weekly CMS publications since Feb 3, 2021.
What are the highest and lowest recorded NADAC prices for LYLLANA 0.025 MG PATCH?
Since Feb 3, 2021, the NADAC for LYLLANA 0.025 MG PATCH has ranged from a low of $4.9692 (Nov 20, 2024) to a high of $10.9520 (Jan 12, 2022), with a median of $6.7114 per EA.
Are there cheaper alternatives to LYLLANA 0.025 MG PATCH?
4 NADAC-published products share the same active ingredient, strength, and dosage form as LYLLANA 0.025 MG PATCH, but none are currently priced below it.
Who manufactures LYLLANA 0.025 MG PATCH?
LYLLANA 0.025 MG PATCH (NDC 65162012608) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.
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