Product Information
LYLLANA 0.1 MG PATCH is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $7.3281 per EA under NDC 65162022808. Its NADAC has been published 282 times since Feb 3, 2021.
Strength
.1 mg/d
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162022808
Classification
Generic
Dosage Form
PATCH, EXTENDED RELEASE
Route
TRANSDERMAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA211396On Market Since
9/30/2020
Pharmacological Classes
Price Statistics
The NADAC for LYLLANA 0.1 MG PATCH has been published 282 times since Feb 3, 2021, and over the history we have for it it has declined 9.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.3281 per EA |
|---|---|
| All-time high | $9.5510 (Jan 12, 2022) |
| All-time low | $5.0152 (Nov 20, 2024) |
| 52-week high | $7.3281 |
| 52-week low | $6.7754 |
| Median price | $6.8704 |
| Average price | $6.9990 |
| Largest weekly change | -24.4% (Nov 20, 2024) |
| Weeks tracked | 282 |
| Tracking since | Feb 3, 2021 |
Generic Alternatives
The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of LYLLANA 0.1 MG PATCH?
The current National Average Drug Acquisition Cost (NADAC) for LYLLANA 0.1 MG PATCH, manufactured by Amneal Pharmaceuticals LLC, is $7.3281 per EA (NDC 65162022808), effective Jun 24, 2026.
How has the price of LYLLANA 0.1 MG PATCH changed over time?
Over the history we have for it, the NADAC for LYLLANA 0.1 MG PATCH has declined 9.2%. It has been tracked across 282 weekly CMS publications since Feb 3, 2021.
What are the highest and lowest recorded NADAC prices for LYLLANA 0.1 MG PATCH?
Since Feb 3, 2021, the NADAC for LYLLANA 0.1 MG PATCH has ranged from a low of $5.0152 (Nov 20, 2024) to a high of $9.5510 (Jan 12, 2022), with a median of $6.8704 per EA.
Are there cheaper alternatives to LYLLANA 0.1 MG PATCH?
4 NADAC-published products share the same active ingredient, strength, and dosage form as LYLLANA 0.1 MG PATCH, but none are currently priced below it.
Who manufactures LYLLANA 0.1 MG PATCH?
LYLLANA 0.1 MG PATCH (NDC 65162022808) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.
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