Product Information

DOTTI 0.1 MG PATCH is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $7.3281 per EA under NDC 65162099708. Its NADAC has been published 364 times since Jul 10, 2019.

DOTTI 0.1 MG PATCH

Estradiol
$7.3281per EA

Strength

.1 mg/d

NDC

65162099708

Classification

Generic

Dosage Form

PATCH, EXTENDED RELEASE

Route

TRANSDERMAL

Last Updated

6/17/2026

Active Ingredients

ESTRADIOL

Approval Type

Generic (ANDA)

FDA Application

ANDA211293

On Market Since

2/4/2019

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for DOTTI 0.1 MG PATCH has been published 364 times since Jul 10, 2019, and over the history we have for it it has declined 7.1%. The table below summarizes its recorded NADAC range and movement.

Current price$7.3281 per EA
All-time high$9.5510 (Jan 12, 2022)
All-time low$5.0152 (Nov 20, 2024)
52-week high$7.3281
52-week low$6.7754
Median price$6.9668
Average price$7.1719
Largest weekly change-24.4% (Nov 20, 2024)
Weeks tracked364
Tracking sinceJul 10, 2019

Price History

1W

0.0%

1M

+3.5%

3M

+8.2%

6M

+6.7%

1Y

+3.2%

3Y

+12.5%

5Y

+6.3%

All

-7.1%

Generic Alternatives

The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DOTTI 0.1 MG PATCH?

The current National Average Drug Acquisition Cost (NADAC) for DOTTI 0.1 MG PATCH, manufactured by Amneal Pharmaceuticals LLC, is $7.3281 per EA (NDC 65162099708), effective Jun 24, 2026.

How has the price of DOTTI 0.1 MG PATCH changed over time?

Over the history we have for it, the NADAC for DOTTI 0.1 MG PATCH has declined 7.1%. It has been tracked across 364 weekly CMS publications since Jul 10, 2019.

What are the highest and lowest recorded NADAC prices for DOTTI 0.1 MG PATCH?

Since Jul 10, 2019, the NADAC for DOTTI 0.1 MG PATCH has ranged from a low of $5.0152 (Nov 20, 2024) to a high of $9.5510 (Jan 12, 2022), with a median of $6.9668 per EA.

Are there cheaper alternatives to DOTTI 0.1 MG PATCH?

4 NADAC-published products share the same active ingredient, strength, and dosage form as DOTTI 0.1 MG PATCH, but none are currently priced below it.

Who manufactures DOTTI 0.1 MG PATCH?

DOTTI 0.1 MG PATCH (NDC 65162099708) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.