Historical record - last NADAC effective date: 2/23/2022

Product Information

ENTECAVIR 0.5 MG TABLET is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $1.0765 per EA under NDC 65162044603. Its NADAC has been published 315 times since Mar 9, 2016.

FDA first approved this application on Nov 12, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the Entecavir market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

ENTECAVIR 0.5 MG TABLET

Entecavir
$1.0765per EA
High Outlier

Strength

.5 mg/1

NDC

65162044603

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

2/23/2022

Active Ingredients

ENTECAVIR

Approval Type

Generic (ANDA)

FDA Application

ANDA206652

FDA Approved

11/12/2015

TE Code

AB

On Market Since

11/28/2014

Pharmacological Classes

Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor
Nucleoside Analog
Nucleoside Reverse Transcriptase Inhibitors

Price Statistics

The NADAC for ENTECAVIR 0.5 MG TABLET has been published 315 times since Mar 9, 2016, and over the history we have for it it has declined 95.4%. The table below summarizes its recorded NADAC range and movement.

Current price$1.0765 per EA
All-time high$23.6432 (Mar 16, 2016)
All-time low$0.8444 (Dec 22, 2021)
Median price$1.9269
Average price$5.0367
Largest weekly change-38.7% (Mar 17, 2021)
Weeks tracked315
Tracking sinceMar 9, 2016

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

N/A

3Y

N/A

5Y

-16.5%

All

-95.4%

Last surveyed Mar 16, 2022 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 80% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ENTECAVIR 0.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ENTECAVIR 0.5 MG TABLET, manufactured by Amneal Pharmaceuticals LLC, is $1.0765 per EA (NDC 65162044603), effective Mar 16, 2022.

How has the price of ENTECAVIR 0.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for ENTECAVIR 0.5 MG TABLET has declined 95.4%. It has been tracked across 315 weekly CMS publications since Mar 9, 2016.

What are the highest and lowest recorded NADAC prices for ENTECAVIR 0.5 MG TABLET?

Since Mar 9, 2016, the NADAC for ENTECAVIR 0.5 MG TABLET has ranged from a low of $0.8444 (Dec 22, 2021) to a high of $23.6432 (Mar 16, 2016), with a median of $1.9269 per EA.

Are there cheaper alternatives to ENTECAVIR 0.5 MG TABLET?

Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ENTECAVIR 0.5 MG TABLET, is $0.2134 per EA — about 80% below ENTECAVIR 0.5 MG TABLET.

Who manufactures ENTECAVIR 0.5 MG TABLET?

ENTECAVIR 0.5 MG TABLET (NDC 65162044603) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.