Product Information

ENTECAVIR 0.5 MG TABLET is a generic product labeled by Epic Pharma LLC, priced at $0.2134 per EA under NDC 42806065830. Its NADAC has been published 297 times since Dec 16, 2020.

FDA first approved this application on Sep 25, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ENTECAVIR 0.5 MG TABLET

Entecavir
$0.2134per EA

Strength

.5 mg/1

Manufacturer

Epic Pharma LLC

NDC

42806065830

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ENTECAVIR

Approval Type

Generic (ANDA)

FDA Application

ANDA212126

FDA Approved

9/25/2019

TE Code

AB

On Market Since

6/2/2020

Pharmacological Classes

Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor
Nucleoside Analog
Nucleoside Reverse Transcriptase Inhibitors

Price Statistics

The NADAC for ENTECAVIR 0.5 MG TABLET has been published 297 times since Dec 16, 2020, and over the history we have for it it has declined 82.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2134 per EA
All-time high$1.5428 (Mar 10, 2021)
All-time low$0.2096 (May 20, 2026)
52-week high$0.2640
52-week low$0.2096
Median price$0.4467
Average price$0.5812
Largest weekly change+48.1% (Jul 17, 2024)
Weeks tracked297
Tracking sinceDec 16, 2020

Price History

1W

+0.1%

1M

+0.1%

3M

+1.8%

6M

-9.2%

1Y

-18.7%

3Y

-52.2%

5Y

-83.4%

All

-82.1%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ENTECAVIR 0.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ENTECAVIR 0.5 MG TABLET, manufactured by Epic Pharma LLC, is $0.2134 per EA (NDC 42806065830), effective Aug 19, 2026.

How has the price of ENTECAVIR 0.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for ENTECAVIR 0.5 MG TABLET has declined 82.1%. It has been tracked across 297 weekly CMS publications since Dec 16, 2020.

What are the highest and lowest recorded NADAC prices for ENTECAVIR 0.5 MG TABLET?

Since Dec 16, 2020, the NADAC for ENTECAVIR 0.5 MG TABLET has ranged from a low of $0.2096 (May 20, 2026) to a high of $1.5428 (Mar 10, 2021), with a median of $0.4467 per EA.

Are there cheaper alternatives to ENTECAVIR 0.5 MG TABLET?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ENTECAVIR 0.5 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures ENTECAVIR 0.5 MG TABLET?

ENTECAVIR 0.5 MG TABLET (NDC 42806065830) is labeled by Epic Pharma LLC, and CMS classifies it as a generic product.