Product Information

ACYCLOVIR 400 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.0985 per EA under NDC 00904750761. Its NADAC has been published 66 times since May 21, 2025.

FDA first approved this application on Oct 29, 2013. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ACYCLOVIR 400 MG TABLET

Acyclovir
$0.0985per EA

Strength

400 mg/1

NDC

00904750761

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ACYCLOVIR

Approval Type

Generic (ANDA)

FDA Application

ANDA203834

FDA Approved

10/29/2013

TE Code

AB

On Market Since

1/28/2025

Price Statistics

The NADAC for ACYCLOVIR 400 MG TABLET has been published 66 times since May 21, 2025, and over the history we have for it it has risen 7.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0985 per EA
All-time high$0.1007 (Jun 10, 2026)
All-time low$0.0912 (Feb 18, 2026)
52-week high$0.1007
52-week low$0.0912
Median price$0.0931
Average price$0.0947
Largest weekly change+5.9% (Mar 18, 2026)
Weeks tracked66
Tracking sinceMay 21, 2025

Price History

1W

-1.5%

1M

-1.5%

3M

-2.2%

6M

+8.0%

1Y

+3.9%

3Y

N/A

5Y

N/A

All

+7.1%

Generic Alternatives

The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 21% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ACYCLOVIR 400 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ACYCLOVIR 400 MG TABLET, manufactured by Major Pharmaceuticals, is $0.0985 per EA (NDC 00904750761), effective Aug 19, 2026.

How has the price of ACYCLOVIR 400 MG TABLET changed over time?

Over the history we have for it, the NADAC for ACYCLOVIR 400 MG TABLET has risen 7.1%. It has been tracked across 66 weekly CMS publications since May 21, 2025.

What are the highest and lowest recorded NADAC prices for ACYCLOVIR 400 MG TABLET?

Since May 21, 2025, the NADAC for ACYCLOVIR 400 MG TABLET has ranged from a low of $0.0912 (Feb 18, 2026) to a high of $0.1007 (Jun 10, 2026), with a median of $0.0931 per EA.

Are there cheaper alternatives to ACYCLOVIR 400 MG TABLET?

Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ACYCLOVIR 400 MG TABLET, is $0.0779 per EA — about 21% below ACYCLOVIR 400 MG TABLET.

Who manufactures ACYCLOVIR 400 MG TABLET?

ACYCLOVIR 400 MG TABLET (NDC 00904750761) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.