Product Information
TOBRAMYCIN 300 MG/5 ML AMPULE is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $1.0840 per ML under NDC 65162091446. Its NADAC has been published 511 times since Oct 19, 2016.
FDA first approved this application on Jul 13, 2015. Its Orange Book therapeutic-equivalence code is AN.
Strength
300 mg/5mL
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162091446
Classification
Generic
Dosage Form
SOLUTION
Route
RESPIRATORY (INHALATION)
Effective Date
9/23/2026
Active Ingredients
TOBRAMYCINApproval Type
Generic (ANDA)
FDA Application
ANDA205501FDA Approved
7/13/2015
TE Code
AN
On Market Since
7/13/2014
Pharmacological Classes
Price Statistics
The NADAC for TOBRAMYCIN 300 MG/5 ML AMPULE has been published 511 times since Oct 19, 2016, and over the history we have for it it has declined 90.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0840 per ML |
|---|---|
| All-time high | $11.5766 (Mar 15, 2017) |
| All-time low | $1.0672 (Mar 18, 2026) |
| 52-week high | $1.4721 |
| 52-week low | $1.0672 |
| Median price | $3.7654 |
| Average price | $4.5152 |
| Largest weekly change | -33.9% (Nov 20, 2024) |
| Weeks tracked | 511 |
| Tracking since | Oct 19, 2016 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Amneal Pharmaceuticals LLC manufacturer profile
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Therapeutic class
Aminoglycoside Antibacterial class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TOBRAMYCIN 300 MG/5 ML AMPULE?
The current National Average Drug Acquisition Cost (NADAC) for TOBRAMYCIN 300 MG/5 ML AMPULE, manufactured by Amneal Pharmaceuticals LLC, is $1.0840 per ML (NDC 65162091446), effective Sep 30, 2026.
How has the price of TOBRAMYCIN 300 MG/5 ML AMPULE changed over time?
Over the history we have for it, the NADAC for TOBRAMYCIN 300 MG/5 ML AMPULE has declined 90.6%. It has been tracked across 511 weekly CMS publications since Oct 19, 2016.
What are the highest and lowest recorded NADAC prices for TOBRAMYCIN 300 MG/5 ML AMPULE?
Since Oct 19, 2016, the NADAC for TOBRAMYCIN 300 MG/5 ML AMPULE has ranged from a low of $1.0672 (Mar 18, 2026) to a high of $11.5766 (Mar 15, 2017), with a median of $3.7654 per ML.
Are there cheaper alternatives to TOBRAMYCIN 300 MG/5 ML AMPULE?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TOBRAMYCIN 300 MG/5 ML AMPULE in a comparable dosage form, but none are currently priced below it.
Who manufactures TOBRAMYCIN 300 MG/5 ML AMPULE?
TOBRAMYCIN 300 MG/5 ML AMPULE (NDC 65162091446) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.