Product Information
TOBRAMYCIN 300 MG/5 ML AMPULE is a generic product labeled by NorthStar Rx LLC, priced at $1.0845 per ML under NDC 72603043056. Its NADAC has been published 69 times since Apr 30, 2025.
FDA first approved this application on Jun 30, 2023. Its Orange Book therapeutic-equivalence code is AN.
Strength
300 mg/5mL
Manufacturer
NorthStar Rx LLCNDC
72603043056
Classification
Generic
Dosage Form
SOLUTION
Route
RESPIRATORY (INHALATION)
Effective Date
8/19/2026
Active Ingredients
TOBRAMYCINApproval Type
Generic (ANDA)
FDA Application
ANDA214478FDA Approved
6/30/2023
TE Code
AN
On Market Since
8/1/2024
Pharmacological Classes
Price Statistics
The NADAC for TOBRAMYCIN 300 MG/5 ML AMPULE has been published 69 times since Apr 30, 2025, and over the history we have for it it has declined 31.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0845 per ML |
|---|---|
| All-time high | $1.7603 (Jul 16, 2025) |
| All-time low | $1.0672 (Mar 18, 2026) |
| 52-week high | $1.6501 |
| 52-week low | $1.0672 |
| Median price | $1.2288 |
| Average price | $1.3286 |
| Largest weekly change | -10.8% (Sep 17, 2025) |
| Weeks tracked | 69 |
| Tracking since | Apr 30, 2025 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TOBRAMYCIN 300 MG/5 ML AMPULE?
The current National Average Drug Acquisition Cost (NADAC) for TOBRAMYCIN 300 MG/5 ML AMPULE, manufactured by NorthStar Rx LLC, is $1.0845 per ML (NDC 72603043056), effective Aug 19, 2026.
How has the price of TOBRAMYCIN 300 MG/5 ML AMPULE changed over time?
Over the history we have for it, the NADAC for TOBRAMYCIN 300 MG/5 ML AMPULE has declined 31.8%. It has been tracked across 69 weekly CMS publications since Apr 30, 2025.
What are the highest and lowest recorded NADAC prices for TOBRAMYCIN 300 MG/5 ML AMPULE?
Since Apr 30, 2025, the NADAC for TOBRAMYCIN 300 MG/5 ML AMPULE has ranged from a low of $1.0672 (Mar 18, 2026) to a high of $1.7603 (Jul 16, 2025), with a median of $1.2288 per ML.
Are there cheaper alternatives to TOBRAMYCIN 300 MG/5 ML AMPULE?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TOBRAMYCIN 300 MG/5 ML AMPULE in a comparable dosage form, but none are currently priced below it.
Who manufactures TOBRAMYCIN 300 MG/5 ML AMPULE?
TOBRAMYCIN 300 MG/5 ML AMPULE (NDC 72603043056) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.