Product Information
AFIRMELLE-28 TABLET is a generic product labeled by Aurobindo Pharma Limited, priced at $0.1584 per EA under NDC 65862084988. Its NADAC has been published 314 times since Aug 21, 2019.
FDA first approved this application on Nov 14, 2016. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Manufacturer
Aurobindo Pharma LimitedNDC
65862084988
Classification
Generic
Dosage Form
KIT
Effective Date
8/20/2025
Approval Type
Generic (ANDA)
FDA Application
ANDA206886FDA Approved
11/14/2016
TE Code
AB1
On Market Since
11/14/2016
Price Statistics
The NADAC for AFIRMELLE-28 TABLET has been published 314 times since Aug 21, 2019, and over the history we have for it it has declined 58.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1584 per EA |
|---|---|
| All-time high | $0.3780 (Sep 11, 2019) |
| All-time low | $0.1212 (Jul 17, 2024) |
| Median price | $0.2057 |
| Average price | $0.2138 |
| Largest weekly change | +35.3% (Jun 19, 2024) |
| Weeks tracked | 314 |
| Tracking since | Aug 21, 2019 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
-13.9%
5Y
-25.5%
All
-58.1%
Last surveyed Aug 20, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 29% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of AFIRMELLE-28 TABLET?
The current National Average Drug Acquisition Cost (NADAC) for AFIRMELLE-28 TABLET, manufactured by Aurobindo Pharma Limited, is $0.1584 per EA (NDC 65862084988), effective Aug 20, 2025.
How has the price of AFIRMELLE-28 TABLET changed over time?
Over the history we have for it, the NADAC for AFIRMELLE-28 TABLET has declined 58.1%. It has been tracked across 314 weekly CMS publications since Aug 21, 2019.
What are the highest and lowest recorded NADAC prices for AFIRMELLE-28 TABLET?
Since Aug 21, 2019, the NADAC for AFIRMELLE-28 TABLET has ranged from a low of $0.1212 (Jul 17, 2024) to a high of $0.3780 (Sep 11, 2019), with a median of $0.2057 per EA.
Are there cheaper alternatives to AFIRMELLE-28 TABLET?
Yes. 9 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CHATEAL EQ-28 TABLET, is $0.1128 per EA — about 29% below AFIRMELLE-28 TABLET.
Who manufactures AFIRMELLE-28 TABLET?
AFIRMELLE-28 TABLET (NDC 65862084988) is labeled by Aurobindo Pharma Limited, and CMS classifies it as a generic product.