Product Information
KRISTALOSE 20 GM PACKET is a brand (anda) product labeled by Cumberland Pharmaceuticals Inc., priced at $9.9154 per EA under NDC 66220072930. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Dec 10, 1997. Its Orange Book therapeutic-equivalence code is AA.
Strength
20 g/20g
Manufacturer
Cumberland Pharmaceuticals Inc.NDC
66220072930
Classification
Brand (ANDA)
Dosage Form
POWDER, FOR SOLUTION
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
LACTULOSEApproval Type
Generic (ANDA)
FDA Application
ANDA074712FDA Approved
12/10/1997
TE Code
AA
On Market Since
1/20/2012
Pharmacological Classes
Price Statistics
The NADAC for KRISTALOSE 20 GM PACKET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 276.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $9.9154 per EA |
|---|---|
| All-time high | $9.9770 (May 13, 2026) |
| All-time low | $2.6330 (Nov 28, 2013) |
| 52-week high | $9.9770 |
| 52-week low | $9.7334 |
| Median price | $7.6997 |
| Average price | $7.6465 |
| Largest weekly change | +124.8% (Jan 22, 2014) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 16% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of KRISTALOSE 20 GM PACKET?
The current National Average Drug Acquisition Cost (NADAC) for KRISTALOSE 20 GM PACKET, manufactured by Cumberland Pharmaceuticals Inc., is $9.9154 per EA (NDC 66220072930), effective Aug 19, 2026.
How has the price of KRISTALOSE 20 GM PACKET changed over time?
Over the history we have for it, the NADAC for KRISTALOSE 20 GM PACKET has risen 276.6%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for KRISTALOSE 20 GM PACKET?
Since Nov 28, 2013, the NADAC for KRISTALOSE 20 GM PACKET has ranged from a low of $2.6330 (Nov 28, 2013) to a high of $9.9770 (May 13, 2026), with a median of $7.6997 per EA.
Are there cheaper alternatives to KRISTALOSE 20 GM PACKET?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LACTULOSE 20 GM PACKET, is $8.3407 per EA — about 16% below KRISTALOSE 20 GM PACKET.
Who manufactures KRISTALOSE 20 GM PACKET?
KRISTALOSE 20 GM PACKET (NDC 66220072930) is labeled by Cumberland Pharmaceuticals Inc., and CMS classifies it as a brand (anda) product.