Product Information

METFORMIN HCL ER 500 MG TABLET is a generic product labeled by Ascend Laboratories, LLC, priced at $0.0288 per EA under NDC 67877041390. Its NADAC has been published 281 times since Apr 7, 2021.

FDA first approved this application on Oct 22, 2018. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METFORMIN HCL ER 500 MG TABLET

Metformin Hydrochloride
$0.0288per EA

Strength

500 mg/1

NDC

67877041390

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

METFORMIN HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA206145

FDA Approved

10/22/2018

TE Code

AB1

On Market Since

10/27/2018

Pharmacological Classes

Biguanide
Biguanides

Price Statistics

The NADAC for METFORMIN HCL ER 500 MG TABLET has been published 281 times since Apr 7, 2021, and over the history we have for it it has declined 18.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0288 per EA
All-time high$0.0445 (Nov 16, 2022)
All-time low$0.0238 (Nov 20, 2024)
52-week high$0.0299
52-week low$0.0288
Median price$0.0319
Average price$0.0328
Largest weekly change+29.1% (Feb 22, 2023)
Weeks tracked281
Tracking sinceApr 7, 2021

Price History

1W

-1.8%

1M

-3.4%

3M

-3.7%

6M

-0.9%

1Y

-3.1%

3Y

-7.9%

5Y

-22.5%

All

-18.2%

Generic Alternatives

The matcher finds 21 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 51% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METFORMIN HCL ER 500 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for METFORMIN HCL ER 500 MG TABLET, manufactured by Ascend Laboratories, LLC, is $0.0288 per EA (NDC 67877041390), effective Aug 19, 2026.

How has the price of METFORMIN HCL ER 500 MG TABLET changed over time?

Over the history we have for it, the NADAC for METFORMIN HCL ER 500 MG TABLET has declined 18.2%. It has been tracked across 281 weekly CMS publications since Apr 7, 2021.

What are the highest and lowest recorded NADAC prices for METFORMIN HCL ER 500 MG TABLET?

Since Apr 7, 2021, the NADAC for METFORMIN HCL ER 500 MG TABLET has ranged from a low of $0.0238 (Nov 20, 2024) to a high of $0.0445 (Nov 16, 2022), with a median of $0.0319 per EA.

Are there cheaper alternatives to METFORMIN HCL ER 500 MG TABLET?

Yes. 21 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METFORMIN HCL 500 MG TABLET, is $0.0142 per EA — about 51% below METFORMIN HCL ER 500 MG TABLET.

Who manufactures METFORMIN HCL ER 500 MG TABLET?

METFORMIN HCL ER 500 MG TABLET (NDC 67877041390) is labeled by Ascend Laboratories, LLC, and CMS classifies it as a generic product.