Product Information

RANOLAZINE ER 500 MG TABLET is a generic product labeled by Ascend Laboratories, LLC, priced at $0.1609 per EA under NDC 67877052560. Its NADAC has been published 264 times since Aug 4, 2021.

FDA first approved this application on Nov 30, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

RANOLAZINE ER 500 MG TABLET

Ranolazine
$0.1609per EA

Strength

500 mg/1

NDC

67877052560

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

RANOLAZINE

Approval Type

Generic (ANDA)

FDA Application

ANDA209953

FDA Approved

11/30/2020

TE Code

AB

On Market Since

12/2/2020

Pharmacological Classes

Anti-anginal
Cytochrome P450 2D6 Inhibitors
Cytochrome P450 3A Inhibitors
Organic Cation Transporter 2 Inhibitors
P-Glycoprotein Inhibitors

Price Statistics

The NADAC for RANOLAZINE ER 500 MG TABLET has been published 264 times since Aug 4, 2021, and over the history we have for it it has declined 58.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1609 per EA
All-time high$0.3830 (Aug 11, 2021)
All-time low$0.1581 (Jul 22, 2026)
52-week high$0.1743
52-week low$0.1581
Median price$0.2152
Average price$0.2287
Largest weekly change+17.6% (Aug 21, 2024)
Weeks tracked264
Tracking sinceAug 4, 2021

Price History

1W

+1.7%

1M

+1.7%

3M

-4.1%

6M

-0.9%

1Y

-7.7%

3Y

-25.0%

5Y

-52.5%

All

-58.0%

Generic Alternatives

The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of RANOLAZINE ER 500 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for RANOLAZINE ER 500 MG TABLET, manufactured by Ascend Laboratories, LLC, is $0.1609 per EA (NDC 67877052560), effective Aug 19, 2026.

How has the price of RANOLAZINE ER 500 MG TABLET changed over time?

Over the history we have for it, the NADAC for RANOLAZINE ER 500 MG TABLET has declined 58.0%. It has been tracked across 264 weekly CMS publications since Aug 4, 2021.

What are the highest and lowest recorded NADAC prices for RANOLAZINE ER 500 MG TABLET?

Since Aug 4, 2021, the NADAC for RANOLAZINE ER 500 MG TABLET has ranged from a low of $0.1581 (Jul 22, 2026) to a high of $0.3830 (Aug 11, 2021), with a median of $0.2152 per EA.

Are there cheaper alternatives to RANOLAZINE ER 500 MG TABLET?

12 manufacturers publish a NADAC-priced product with the same active ingredient and strength as RANOLAZINE ER 500 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures RANOLAZINE ER 500 MG TABLET?

RANOLAZINE ER 500 MG TABLET (NDC 67877052560) is labeled by Ascend Laboratories, LLC, and CMS classifies it as a generic product.