Product Information
RANOLAZINE ER 500 MG TABLET is a generic product labeled by Ascend Laboratories, LLC, priced at $0.1649 per EA under NDC 67877052560. Its NADAC has been published 270 times since Aug 4, 2021.
FDA first approved this application on Nov 30, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Ascend Laboratories, LLCNDC
67877052560
Classification
Generic
Dosage Form
TABLET, FILM COATED, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
RANOLAZINEApproval Type
Generic (ANDA)
FDA Application
ANDA209953FDA Approved
11/30/2020
TE Code
AB
On Market Since
12/2/2020
Pharmacological Classes
Price Statistics
The NADAC for RANOLAZINE ER 500 MG TABLET has been published 270 times since Aug 4, 2021, and over the history we have for it it has declined 56.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1649 per EA |
|---|---|
| All-time high | $0.3830 (Aug 11, 2021) |
| All-time low | $0.1581 (Jul 22, 2026) |
| 52-week high | $0.1691 |
| 52-week low | $0.1581 |
| Median price | $0.2152 |
| Average price | $0.2272 |
| Largest weekly change | +17.6% (Aug 21, 2024) |
| Weeks tracked | 270 |
| Tracking since | Aug 4, 2021 |
Generic Alternatives
The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 2% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Ascend Laboratories, LLC manufacturer profile
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Drug market
Ranolazine market comparison
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Therapeutic class
Anti-anginal class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of RANOLAZINE ER 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for RANOLAZINE ER 500 MG TABLET, manufactured by Ascend Laboratories, LLC, is $0.1649 per EA (NDC 67877052560), effective Sep 30, 2026.
How has the price of RANOLAZINE ER 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for RANOLAZINE ER 500 MG TABLET has declined 56.9%. It has been tracked across 270 weekly CMS publications since Aug 4, 2021.
What are the highest and lowest recorded NADAC prices for RANOLAZINE ER 500 MG TABLET?
Since Aug 4, 2021, the NADAC for RANOLAZINE ER 500 MG TABLET has ranged from a low of $0.1581 (Jul 22, 2026) to a high of $0.3830 (Aug 11, 2021), with a median of $0.2152 per EA.
Are there cheaper alternatives to RANOLAZINE ER 500 MG TABLET?
Yes. 12 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, RANOLAZINE ER 500 MG TABLET, is $0.1609 per EA — about 2% below RANOLAZINE ER 500 MG TABLET.
Who manufactures RANOLAZINE ER 500 MG TABLET?
RANOLAZINE ER 500 MG TABLET (NDC 67877052560) is labeled by Ascend Laboratories, LLC, and CMS classifies it as a generic product.