Product Information

SERTRALINE HCL 50 MG TABLET is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.0345 per EA under NDC 68180035209. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Feb 6, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

SERTRALINE HCL 50 MG TABLET

Sertraline Hydrochloride
$0.0345per EA

Strength

50 mg/1

NDC

68180035209

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

SERTRALINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA077670

FDA Approved

2/6/2007

TE Code

AB

On Market Since

2/6/2007

Pharmacological Classes

Cytochrome P450 2D6 Inhibitors
Serotonin Reuptake Inhibitor
Serotonin Uptake Inhibitors

Price Statistics

The NADAC for SERTRALINE HCL 50 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 31.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0345 per EA
All-time high$0.0691 (Aug 12, 2020)
All-time low$0.0292 (Nov 20, 2024)
52-week high$0.0388
52-week low$0.0343
Median price$0.0452
Average price$0.0458
Largest weekly change+57.1% (Jul 22, 2020)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-0.7%

1M

-0.7%

3M

-0.3%

6M

-4.9%

1Y

-4.4%

3Y

-24.9%

5Y

-28.5%

All

-31.9%

Generic Alternatives

The matcher finds 8 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SERTRALINE HCL 50 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SERTRALINE HCL 50 MG TABLET, manufactured by Lupin Pharmaceuticals Inc., is $0.0345 per EA (NDC 68180035209), effective Aug 19, 2026.

How has the price of SERTRALINE HCL 50 MG TABLET changed over time?

Over the history we have for it, the NADAC for SERTRALINE HCL 50 MG TABLET has declined 31.9%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for SERTRALINE HCL 50 MG TABLET?

Since Nov 28, 2013, the NADAC for SERTRALINE HCL 50 MG TABLET has ranged from a low of $0.0292 (Nov 20, 2024) to a high of $0.0691 (Aug 12, 2020), with a median of $0.0452 per EA.

Are there cheaper alternatives to SERTRALINE HCL 50 MG TABLET?

8 manufacturers publish a NADAC-priced product with the same active ingredient and strength as SERTRALINE HCL 50 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures SERTRALINE HCL 50 MG TABLET?

SERTRALINE HCL 50 MG TABLET (NDC 68180035209) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.