Product Information
TRAMADOL HCL ER 100 MG TABLET is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.8943 per EA under NDC 68180069706. Its NADAC has been published 631 times since Sep 3, 2014.
FDA first approved this application on Aug 29, 2011. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100 mg/1
Manufacturer
Lupin Pharmaceuticals Inc.NDC
68180069706
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
TRAMADOL HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA200503FDA Approved
8/29/2011
TE Code
AB1
On Market Since
8/19/2014
Pharmacological Classes
Price Statistics
The NADAC for TRAMADOL HCL ER 100 MG TABLET has been published 631 times since Sep 3, 2014, and over the history we have for it it has declined 59.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.8943 per EA |
|---|---|
| All-time high | $2.4671 (Mar 11, 2015) |
| All-time low | $0.7905 (Sep 21, 2022) |
| 52-week high | $1.0796 |
| 52-week low | $0.8943 |
| Median price | $1.2235 |
| Average price | $1.3918 |
| Largest weekly change | +45.3% (Dec 19, 2018) |
| Weeks tracked | 631 |
| Tracking since | Sep 3, 2014 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Lupin Pharmaceuticals Inc. manufacturer profile
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Drug market
TRAMADOL HYDROCHLORIDE market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TRAMADOL HCL ER 100 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for TRAMADOL HCL ER 100 MG TABLET, manufactured by Lupin Pharmaceuticals Inc., is $0.8943 per EA (NDC 68180069706), effective Sep 30, 2026.
How has the price of TRAMADOL HCL ER 100 MG TABLET changed over time?
Over the history we have for it, the NADAC for TRAMADOL HCL ER 100 MG TABLET has declined 59.8%. It has been tracked across 631 weekly CMS publications since Sep 3, 2014.
What are the highest and lowest recorded NADAC prices for TRAMADOL HCL ER 100 MG TABLET?
Since Sep 3, 2014, the NADAC for TRAMADOL HCL ER 100 MG TABLET has ranged from a low of $0.7905 (Sep 21, 2022) to a high of $2.4671 (Mar 11, 2015), with a median of $1.2235 per EA.
Are there cheaper alternatives to TRAMADOL HCL ER 100 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as TRAMADOL HCL ER 100 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures TRAMADOL HCL ER 100 MG TABLET?
TRAMADOL HCL ER 100 MG TABLET (NDC 68180069706) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.