Product Information

CLOBETASOL 0.05% SHAMPOO is a generic product labeled by Mayne Pharma, priced at $0.2208 per ML under NDC 68308066404. Its NADAC has been published 129 times since Mar 6, 2024.

FDA first approved this application on Feb 5, 2004. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CLOBETASOL 0.05% SHAMPOO

clobetasol propionate

$0.2208per ML

Strength

.05 g/100mL

Manufacturer

Mayne Pharma

NDC

68308066404

Classification

Generic

Dosage Form

SHAMPOO

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

CLOBETASOL PROPIONATE

Approval Type

Authorized Generic (NDA)

FDA Application

NDA021644

FDA Approved

2/5/2004

TE Code

On Market Since

11/3/2023

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists

Corticosteroid

Price Statistics

The NADAC for CLOBETASOL 0.05% SHAMPOO has been published 129 times since Mar 6, 2024, and over the history we have for it it has declined 32.5%. The table below summarizes its recorded NADAC range and movement.

Current price	$0.2208 per ML
All-time high	$0.3886 (Jul 10, 2024)
All-time low	$0.2015 (Feb 18, 2026)
52-week high	$0.2612
52-week low	$0.2015
Median price	$0.2359
Average price	$0.2553
Largest weekly change	+42.8% (Jun 19, 2024)
Weeks tracked	129
Tracking since	Mar 6, 2024

Price History

-4.5%

-10.0%

+9.6%

-15.4%

N/A

All

-32.5%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the clobetasol propionate market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

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Frequently asked questions

What is the NADAC price of CLOBETASOL 0.05% SHAMPOO?

The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% SHAMPOO, manufactured by Mayne Pharma, is $0.2208 per ML (NDC 68308066404), effective Aug 19, 2026.

How has the price of CLOBETASOL 0.05% SHAMPOO changed over time?

Over the history we have for it, the NADAC for CLOBETASOL 0.05% SHAMPOO has declined 32.5%. It has been tracked across 129 weekly CMS publications since Mar 6, 2024.

What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% SHAMPOO?

Since Mar 6, 2024, the NADAC for CLOBETASOL 0.05% SHAMPOO has ranged from a low of $0.2015 (Feb 18, 2026) to a high of $0.3886 (Jul 10, 2024), with a median of $0.2359 per ML.

Are there cheaper alternatives to CLOBETASOL 0.05% SHAMPOO?

No other NADAC-published product currently shares the active ingredient and strength of CLOBETASOL 0.05% SHAMPOO in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures CLOBETASOL 0.05% SHAMPOO?

CLOBETASOL 0.05% SHAMPOO (NDC 68308066404) is labeled by Mayne Pharma, and CMS classifies it as a generic product.