Product Information
MEMANTINE HCL ER 21 MG CAPSULE is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $0.3246 per EA under NDC 68382054806. Its NADAC has been published 317 times since Jul 29, 2020.
FDA first approved this application on Aug 3, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
21 mg/1
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
68382054806
Classification
Generic
Dosage Form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
MEMANTINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA203293FDA Approved
8/3/2017
TE Code
AB
On Market Since
4/8/2018
Pharmacological Classes
Price Statistics
The NADAC for MEMANTINE HCL ER 21 MG CAPSULE has been published 317 times since Jul 29, 2020, and over the history we have for it it has declined 83.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3246 per EA |
|---|---|
| All-time high | $2.6229 (Oct 14, 2020) |
| All-time low | $0.3021 (Dec 17, 2025) |
| 52-week high | $0.3933 |
| 52-week low | $0.3021 |
| Median price | $0.6489 |
| Average price | $0.8720 |
| Largest weekly change | +71.8% (Oct 19, 2022) |
| Weeks tracked | 317 |
| Tracking since | Jul 29, 2020 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Memantine hydrochloride market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of MEMANTINE HCL ER 21 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for MEMANTINE HCL ER 21 MG CAPSULE, manufactured by Zydus Pharmaceuticals (USA) Inc., is $0.3246 per EA (NDC 68382054806), effective Aug 19, 2026.
How has the price of MEMANTINE HCL ER 21 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for MEMANTINE HCL ER 21 MG CAPSULE has declined 83.2%. It has been tracked across 317 weekly CMS publications since Jul 29, 2020.
What are the highest and lowest recorded NADAC prices for MEMANTINE HCL ER 21 MG CAPSULE?
Since Jul 29, 2020, the NADAC for MEMANTINE HCL ER 21 MG CAPSULE has ranged from a low of $0.3021 (Dec 17, 2025) to a high of $2.6229 (Oct 14, 2020), with a median of $0.6489 per EA.
Are there cheaper alternatives to MEMANTINE HCL ER 21 MG CAPSULE?
No other NADAC-published product currently shares the active ingredient and strength of MEMANTINE HCL ER 21 MG CAPSULE in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures MEMANTINE HCL ER 21 MG CAPSULE?
MEMANTINE HCL ER 21 MG CAPSULE (NDC 68382054806) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.