Product Information
LIOTHYRONINE SOD 50 MCG TAB is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $0.3622 per EA under NDC 68382058401. Its NADAC has been published 289 times since Mar 24, 2021.
FDA first approved this application on Jan 22, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 ug/1
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
68382058401
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
LIOTHYRONINE SODIUMApproval Type
Generic (ANDA)
FDA Application
ANDA214803FDA Approved
1/22/2021
TE Code
AB
On Market Since
2/1/2021
Pharmacological Classes
Price Statistics
The NADAC for LIOTHYRONINE SOD 50 MCG TAB has been published 289 times since Mar 24, 2021, and over the history we have for it it has declined 58.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3622 per EA |
|---|---|
| All-time high | $1.1422 (Jun 16, 2021) |
| All-time low | $0.3361 (May 20, 2026) |
| 52-week high | $0.4689 |
| 52-week low | $0.3361 |
| Median price | $0.6241 |
| Average price | $0.6138 |
| Largest weekly change | -42.2% (Dec 21, 2022) |
| Weeks tracked | 289 |
| Tracking since | Mar 24, 2021 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Zydus Pharmaceuticals (USA) Inc. manufacturer profile
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Drug market
Liothyronine sodium market comparison
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Therapeutic class
l-Triiodothyronine class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LIOTHYRONINE SOD 50 MCG TAB?
The current National Average Drug Acquisition Cost (NADAC) for LIOTHYRONINE SOD 50 MCG TAB, manufactured by Zydus Pharmaceuticals (USA) Inc., is $0.3622 per EA (NDC 68382058401), effective Sep 30, 2026.
How has the price of LIOTHYRONINE SOD 50 MCG TAB changed over time?
Over the history we have for it, the NADAC for LIOTHYRONINE SOD 50 MCG TAB has declined 58.4%. It has been tracked across 289 weekly CMS publications since Mar 24, 2021.
What are the highest and lowest recorded NADAC prices for LIOTHYRONINE SOD 50 MCG TAB?
Since Mar 24, 2021, the NADAC for LIOTHYRONINE SOD 50 MCG TAB has ranged from a low of $0.3361 (May 20, 2026) to a high of $1.1422 (Jun 16, 2021), with a median of $0.6241 per EA.
Are there cheaper alternatives to LIOTHYRONINE SOD 50 MCG TAB?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LIOTHYRONINE SOD 50 MCG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures LIOTHYRONINE SOD 50 MCG TAB?
LIOTHYRONINE SOD 50 MCG TAB (NDC 68382058401) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.