Product Information
DOXYCYCLINE MONO 50 MG CAP is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $0.1517 per EA under NDC 68382078201. Its NADAC has been published 526 times since Sep 7, 2016.
FDA first approved this application on Feb 18, 2016. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
68382078201
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
DOXYCYCLINEApproval Type
Generic (ANDA)
FDA Application
ANDA205115FDA Approved
2/18/2016
TE Code
AB
On Market Since
3/14/2016
Pharmacological Classes
Price Statistics
The NADAC for DOXYCYCLINE MONO 50 MG CAP has been published 526 times since Sep 7, 2016, and over the history we have for it it has declined 40.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1517 per EA |
|---|---|
| All-time high | $0.3158 (Oct 12, 2016) |
| All-time low | $0.1412 (Jul 17, 2024) |
| 52-week high | $0.1657 |
| 52-week low | $0.1502 |
| Median price | $0.1991 |
| Average price | $0.2069 |
| Largest weekly change | +55.8% (Oct 20, 2021) |
| Weeks tracked | 526 |
| Tracking since | Sep 7, 2016 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
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Manufacturer
Zydus Pharmaceuticals (USA) Inc. manufacturer profile
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Drug market
doxycycline market comparison
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Therapeutic class
Tetracycline-class Drug class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DOXYCYCLINE MONO 50 MG CAP?
The current National Average Drug Acquisition Cost (NADAC) for DOXYCYCLINE MONO 50 MG CAP, manufactured by Zydus Pharmaceuticals (USA) Inc., is $0.1517 per EA (NDC 68382078201), effective Sep 30, 2026.
How has the price of DOXYCYCLINE MONO 50 MG CAP changed over time?
Over the history we have for it, the NADAC for DOXYCYCLINE MONO 50 MG CAP has declined 40.1%. It has been tracked across 526 weekly CMS publications since Sep 7, 2016.
What are the highest and lowest recorded NADAC prices for DOXYCYCLINE MONO 50 MG CAP?
Since Sep 7, 2016, the NADAC for DOXYCYCLINE MONO 50 MG CAP has ranged from a low of $0.1412 (Jul 17, 2024) to a high of $0.3158 (Oct 12, 2016), with a median of $0.1991 per EA.
Are there cheaper alternatives to DOXYCYCLINE MONO 50 MG CAP?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DOXYCYCLINE MONO 50 MG CAP in a comparable dosage form, but none are currently priced below it.
Who manufactures DOXYCYCLINE MONO 50 MG CAP?
DOXYCYCLINE MONO 50 MG CAP (NDC 68382078201) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.