Product Information

LAMOTRIGINE ER 250 MG TABLET is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $1.2532 per EA under NDC 68382098306. Its NADAC has been published 287 times since Feb 24, 2021.

FDA first approved this application on Apr 1, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

LAMOTRIGINE ER 250 MG TABLET

Lamotrigine
$1.2532per EA

Strength

250 mg/1

NDC

68382098306

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

LAMOTRIGINE

Approval Type

Generic (ANDA)

FDA Application

ANDA207763

FDA Approved

4/1/2020

TE Code

AB

On Market Since

5/14/2020

Pharmacological Classes

Anti-epileptic Agent
Decreased Central Nervous System Disorganized Electrical Activity
Dihydrofolate Reductase Inhibitors
Mood Stabilizer
Organic Cation Transporter 2 Inhibitors

Price Statistics

The NADAC for LAMOTRIGINE ER 250 MG TABLET has been published 287 times since Feb 24, 2021, and over the history we have for it it has declined 80.1%. The table below summarizes its recorded NADAC range and movement.

Current price$1.2532 per EA
All-time high$8.3073 (Oct 13, 2021)
All-time low$1.1070 (Nov 19, 2025)
52-week high$1.3127
52-week low$1.1070
Median price$2.5134
Average price$3.2561
Largest weekly change+56.5% (Aug 21, 2024)
Weeks tracked287
Tracking sinceFeb 24, 2021

Price History

1W

-1.9%

1M

-1.9%

3M

+0.4%

6M

-4.5%

1Y

+1.2%

3Y

-51.4%

5Y

-82.8%

All

-80.1%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LAMOTRIGINE ER 250 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for LAMOTRIGINE ER 250 MG TABLET, manufactured by Zydus Pharmaceuticals (USA) Inc., is $1.2532 per EA (NDC 68382098306), effective Aug 19, 2026.

How has the price of LAMOTRIGINE ER 250 MG TABLET changed over time?

Over the history we have for it, the NADAC for LAMOTRIGINE ER 250 MG TABLET has declined 80.1%. It has been tracked across 287 weekly CMS publications since Feb 24, 2021.

What are the highest and lowest recorded NADAC prices for LAMOTRIGINE ER 250 MG TABLET?

Since Feb 24, 2021, the NADAC for LAMOTRIGINE ER 250 MG TABLET has ranged from a low of $1.1070 (Nov 19, 2025) to a high of $8.3073 (Oct 13, 2021), with a median of $2.5134 per EA.

Are there cheaper alternatives to LAMOTRIGINE ER 250 MG TABLET?

4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LAMOTRIGINE ER 250 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures LAMOTRIGINE ER 250 MG TABLET?

LAMOTRIGINE ER 250 MG TABLET (NDC 68382098306) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.