Product Information
LAMOTRIGINE ER 250 MG TABLET is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $1.3026 per EA under NDC 68382098306. Its NADAC has been published 293 times since Feb 24, 2021.
FDA first approved this application on Apr 1, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
250 mg/1
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
68382098306
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
LAMOTRIGINEApproval Type
Generic (ANDA)
FDA Application
ANDA207763FDA Approved
4/1/2020
TE Code
AB
On Market Since
5/14/2020
Pharmacological Classes
Price Statistics
The NADAC for LAMOTRIGINE ER 250 MG TABLET has been published 293 times since Feb 24, 2021, and over the history we have for it it has declined 79.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.3026 per EA |
|---|---|
| All-time high | $8.3073 (Oct 13, 2021) |
| All-time low | $1.1070 (Nov 19, 2025) |
| 52-week high | $1.3127 |
| 52-week low | $1.1070 |
| Median price | $2.5134 |
| Average price | $3.2154 |
| Largest weekly change | +56.5% (Aug 21, 2024) |
| Weeks tracked | 293 |
| Tracking since | Feb 24, 2021 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Zydus Pharmaceuticals (USA) Inc. manufacturer profile
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Drug market
Lamotrigine market comparison
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Therapeutic class
Anti-epileptic Agent class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LAMOTRIGINE ER 250 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for LAMOTRIGINE ER 250 MG TABLET, manufactured by Zydus Pharmaceuticals (USA) Inc., is $1.3026 per EA (NDC 68382098306), effective Sep 30, 2026.
How has the price of LAMOTRIGINE ER 250 MG TABLET changed over time?
Over the history we have for it, the NADAC for LAMOTRIGINE ER 250 MG TABLET has declined 79.3%. It has been tracked across 293 weekly CMS publications since Feb 24, 2021.
What are the highest and lowest recorded NADAC prices for LAMOTRIGINE ER 250 MG TABLET?
Since Feb 24, 2021, the NADAC for LAMOTRIGINE ER 250 MG TABLET has ranged from a low of $1.1070 (Nov 19, 2025) to a high of $8.3073 (Oct 13, 2021), with a median of $2.5134 per EA.
Are there cheaper alternatives to LAMOTRIGINE ER 250 MG TABLET?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LAMOTRIGINE ER 250 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures LAMOTRIGINE ER 250 MG TABLET?
LAMOTRIGINE ER 250 MG TABLET (NDC 68382098306) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.