Product Information

PROPAFENONE HCL ER 225 MG CAP is a generic product labeled by Glenmark Pharmaceuticals Inc., USA, priced at $0.3557 per EA under NDC 68462040860. Its NADAC has been published 451 times since Jan 3, 2018.

FDA first approved this application on Sep 8, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

PROPAFENONE HCL ER 225 MG CAP

propafenone hydrochloride
$0.3557per EA

Strength

225 mg/1

NDC

68462040860

Classification

Generic

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

PROPAFENONE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA205268

FDA Approved

9/8/2017

TE Code

AB

On Market Since

9/8/2017

Pharmacological Classes

Price Statistics

The NADAC for PROPAFENONE HCL ER 225 MG CAP has been published 451 times since Jan 3, 2018, and over the history we have for it it has declined 91.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3557 per EA
All-time high$4.2056 (Jan 10, 2018)
All-time low$0.3001 (May 20, 2026)
52-week high$0.4941
52-week low$0.3001
Median price$1.0333
Average price$1.5813
Largest weekly change+74.3% (Aug 18, 2021)
Weeks tracked451
Tracking sinceJan 3, 2018

Price History

1W

+2.6%

1M

+2.6%

3M

+18.5%

6M

+1.5%

1Y

-28.0%

3Y

-49.6%

5Y

-78.0%

All

-91.5%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PROPAFENONE HCL ER 225 MG CAP?

The current National Average Drug Acquisition Cost (NADAC) for PROPAFENONE HCL ER 225 MG CAP, manufactured by Glenmark Pharmaceuticals Inc., USA, is $0.3557 per EA (NDC 68462040860), effective Aug 19, 2026.

How has the price of PROPAFENONE HCL ER 225 MG CAP changed over time?

Over the history we have for it, the NADAC for PROPAFENONE HCL ER 225 MG CAP has declined 91.5%. It has been tracked across 451 weekly CMS publications since Jan 3, 2018.

What are the highest and lowest recorded NADAC prices for PROPAFENONE HCL ER 225 MG CAP?

Since Jan 3, 2018, the NADAC for PROPAFENONE HCL ER 225 MG CAP has ranged from a low of $0.3001 (May 20, 2026) to a high of $4.2056 (Jan 10, 2018), with a median of $1.0333 per EA.

Are there cheaper alternatives to PROPAFENONE HCL ER 225 MG CAP?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROPAFENONE HCL ER 225 MG CAP in a comparable dosage form, but none are currently priced below it.

Who manufactures PROPAFENONE HCL ER 225 MG CAP?

PROPAFENONE HCL ER 225 MG CAP (NDC 68462040860) is labeled by Glenmark Pharmaceuticals Inc., USA, and CMS classifies it as a generic product.