Product Information
PROPAFENONE HCL ER 225 MG CAP is a generic product labeled by NorthStar Rx LLC, priced at $0.3557 per EA under NDC 16714082501. Its NADAC has been published 354 times since Nov 13, 2019.
FDA first approved this application on Sep 8, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
225 mg/1
Manufacturer
NorthStar Rx LLCNDC
16714082501
Classification
Generic
Dosage Form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
PROPAFENONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA205268FDA Approved
9/8/2017
TE Code
AB
On Market Since
3/31/2017
Pharmacological Classes
Price Statistics
The NADAC for PROPAFENONE HCL ER 225 MG CAP has been published 354 times since Nov 13, 2019, and over the history we have for it it has declined 87.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3557 per EA |
|---|---|
| All-time high | $2.9387 (Jul 15, 2020) |
| All-time low | $0.3001 (May 20, 2026) |
| 52-week high | $0.4941 |
| 52-week low | $0.3001 |
| Median price | $0.8377 |
| Average price | $1.0889 |
| Largest weekly change | +74.3% (Aug 18, 2021) |
| Weeks tracked | 354 |
| Tracking since | Nov 13, 2019 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PROPAFENONE HCL ER 225 MG CAP?
The current National Average Drug Acquisition Cost (NADAC) for PROPAFENONE HCL ER 225 MG CAP, manufactured by NorthStar Rx LLC, is $0.3557 per EA (NDC 16714082501), effective Aug 19, 2026.
How has the price of PROPAFENONE HCL ER 225 MG CAP changed over time?
Over the history we have for it, the NADAC for PROPAFENONE HCL ER 225 MG CAP has declined 87.0%. It has been tracked across 354 weekly CMS publications since Nov 13, 2019.
What are the highest and lowest recorded NADAC prices for PROPAFENONE HCL ER 225 MG CAP?
Since Nov 13, 2019, the NADAC for PROPAFENONE HCL ER 225 MG CAP has ranged from a low of $0.3001 (May 20, 2026) to a high of $2.9387 (Jul 15, 2020), with a median of $0.8377 per EA.
Are there cheaper alternatives to PROPAFENONE HCL ER 225 MG CAP?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROPAFENONE HCL ER 225 MG CAP in a comparable dosage form, but none are currently priced below it.
Who manufactures PROPAFENONE HCL ER 225 MG CAP?
PROPAFENONE HCL ER 225 MG CAP (NDC 16714082501) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.