Product Information

METFORMIN HCL ER 500 MG TABLET is a generic product labeled by Legacy Pharmaceutical Packaging, LLC, priced at $0.0288 per EA under NDC 68645059559. Its NADAC has been published 209 times since Aug 24, 2022.

FDA first approved this application on Mar 16, 2018. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METFORMIN HCL ER 500 MG TABLET

Metformin ER 500 mg
$0.0288per EA

Strength

500 mg/1

NDC

68645059559

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

METFORMIN HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA209313

FDA Approved

3/16/2018

TE Code

AB1

On Market Since

3/10/2022

Pharmacological Classes

Biguanide
Biguanides

Price Statistics

The NADAC for METFORMIN HCL ER 500 MG TABLET has been published 209 times since Aug 24, 2022, and over the history we have for it it has declined 23.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0288 per EA
All-time high$0.0445 (Nov 16, 2022)
All-time low$0.0238 (Nov 20, 2024)
52-week high$0.0299
52-week low$0.0288
Median price$0.0299
Average price$0.0313
Largest weekly change+29.1% (Feb 22, 2023)
Weeks tracked209
Tracking sinceAug 24, 2022

Price History

1W

-1.8%

1M

-1.8%

3M

-3.7%

6M

-0.9%

1Y

-3.1%

3Y

-7.9%

5Y

N/A

All

-23.8%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METFORMIN HCL ER 500 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for METFORMIN HCL ER 500 MG TABLET, manufactured by Legacy Pharmaceutical Packaging, LLC, is $0.0288 per EA (NDC 68645059559), effective Aug 19, 2026.

How has the price of METFORMIN HCL ER 500 MG TABLET changed over time?

Over the history we have for it, the NADAC for METFORMIN HCL ER 500 MG TABLET has declined 23.8%. It has been tracked across 209 weekly CMS publications since Aug 24, 2022.

What are the highest and lowest recorded NADAC prices for METFORMIN HCL ER 500 MG TABLET?

Since Aug 24, 2022, the NADAC for METFORMIN HCL ER 500 MG TABLET has ranged from a low of $0.0238 (Nov 20, 2024) to a high of $0.0445 (Nov 16, 2022), with a median of $0.0299 per EA.

Are there cheaper alternatives to METFORMIN HCL ER 500 MG TABLET?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METFORMIN HCL ER 500 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures METFORMIN HCL ER 500 MG TABLET?

METFORMIN HCL ER 500 MG TABLET (NDC 68645059559) is labeled by Legacy Pharmaceutical Packaging, LLC, and CMS classifies it as a generic product.