Product Information
DIFLUPREDNATE 0.05% EYE DROP is a generic product labeled by Cipla USA Inc., priced at $9.7858 per ML under NDC 69097034135. Its NADAC has been published 218 times since Dec 22, 2021.
FDA first approved this application on Aug 9, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/mL
Manufacturer
Cipla USA Inc.NDC
69097034135
Classification
Generic
Dosage Form
EMULSION
Route
OPHTHALMIC
Effective Date
2/18/2026
Active Ingredients
DIFLUPREDNATEApproval Type
Generic (ANDA)
FDA Application
ANDA211776FDA Approved
8/9/2021
TE Code
AB
On Market Since
8/9/2021
Price Statistics
The NADAC for DIFLUPREDNATE 0.05% EYE DROP has been published 218 times since Dec 22, 2021, and over the history we have for it it has declined 70.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $9.7858 per ML |
|---|---|
| All-time high | $33.3087 (Jan 12, 2022) |
| All-time low | $9.7858 (Feb 18, 2026) |
| 52-week high | $11.3753 |
| 52-week low | $9.7858 |
| Median price | $15.9321 |
| Average price | $17.1853 |
| Largest weekly change | +46.0% (Aug 21, 2024) |
| Weeks tracked | 218 |
| Tracking since | Dec 22, 2021 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
-14.0%
3Y
-48.3%
5Y
N/A
All
-70.6%
Last surveyed Feb 18, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 9% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DIFLUPREDNATE 0.05% EYE DROP?
The current National Average Drug Acquisition Cost (NADAC) for DIFLUPREDNATE 0.05% EYE DROP, manufactured by Cipla USA Inc., is $9.7858 per ML (NDC 69097034135), effective Feb 18, 2026.
How has the price of DIFLUPREDNATE 0.05% EYE DROP changed over time?
Over the history we have for it, the NADAC for DIFLUPREDNATE 0.05% EYE DROP has declined 70.6%. It has been tracked across 218 weekly CMS publications since Dec 22, 2021.
What are the highest and lowest recorded NADAC prices for DIFLUPREDNATE 0.05% EYE DROP?
Since Dec 22, 2021, the NADAC for DIFLUPREDNATE 0.05% EYE DROP has ranged from a low of $9.7858 (Feb 18, 2026) to a high of $33.3087 (Jan 12, 2022), with a median of $15.9321 per ML.
Are there cheaper alternatives to DIFLUPREDNATE 0.05% EYE DROP?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DIFLUPREDNATE 0.05% EYE DROP, is $8.9184 per ML — about 9% below DIFLUPREDNATE 0.05% EYE DROP.
Who manufactures DIFLUPREDNATE 0.05% EYE DROP?
DIFLUPREDNATE 0.05% EYE DROP (NDC 69097034135) is labeled by Cipla USA Inc., and CMS classifies it as a generic product.