Product Information
DIFLUPREDNATE 0.05% EYE DROP is a generic product labeled by Cipla USA Inc., priced at $9.7858 per ML under NDC 69097034135. Its NADAC has been published 218 times since Dec 22, 2021.
FDA first approved this application on Aug 9, 2021.
Strength
.5 mg/mL
Manufacturer
Cipla USA Inc.NDC
69097034135
Classification
Generic
Dosage Form
EMULSION
Route
OPHTHALMIC
Effective Date
2/18/2026
Active Ingredients
DIFLUPREDNATEApproval Type
Generic (ANDA)
FDA Application
ANDA211776FDA Approved
8/9/2021
On Market Since
8/9/2021
Price Statistics
The NADAC for DIFLUPREDNATE 0.05% EYE DROP has been published 218 times since Dec 22, 2021, and over the history we have for it it has declined 70.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $9.7858 per ML |
|---|---|
| All-time high | $33.3087 (Jan 12, 2022) |
| All-time low | $9.7858 (Feb 18, 2026) |
| 52-week high | $10.4599 |
| 52-week low | $9.7858 |
| Median price | $15.9321 |
| Average price | $17.1853 |
| Largest weekly change | +46.0% (Aug 21, 2024) |
| Weeks tracked | 218 |
| Tracking since | Dec 22, 2021 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
-5.1%
3Y
-35.8%
5Y
N/A
All
-70.6%
Last surveyed Feb 18, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Cipla USA Inc. manufacturer profile
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Drug market
DIFLUPREDNATE market comparison
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DIFLUPREDNATE 0.05% EYE DROP?
The current National Average Drug Acquisition Cost (NADAC) for DIFLUPREDNATE 0.05% EYE DROP, manufactured by Cipla USA Inc., is $9.7858 per ML (NDC 69097034135), effective Feb 18, 2026.
How has the price of DIFLUPREDNATE 0.05% EYE DROP changed over time?
Over the history we have for it, the NADAC for DIFLUPREDNATE 0.05% EYE DROP has declined 70.6%. It has been tracked across 218 weekly CMS publications since Dec 22, 2021.
What are the highest and lowest recorded NADAC prices for DIFLUPREDNATE 0.05% EYE DROP?
Since Dec 22, 2021, the NADAC for DIFLUPREDNATE 0.05% EYE DROP has ranged from a low of $9.7858 (Feb 18, 2026) to a high of $33.3087 (Jan 12, 2022), with a median of $15.9321 per ML.
Are there cheaper alternatives to DIFLUPREDNATE 0.05% EYE DROP?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DIFLUPREDNATE 0.05% EYE DROP, is $9.6866 per ML — about 1% below DIFLUPREDNATE 0.05% EYE DROP.
Who manufactures DIFLUPREDNATE 0.05% EYE DROP?
DIFLUPREDNATE 0.05% EYE DROP (NDC 69097034135) is labeled by Cipla USA Inc., and CMS classifies it as a generic product.