Product Information
CLOBETASOL 0.05% CREAM is a generic product labeled by Amneal Pharmaceuticals NY LLC, priced at $0.1930 per GM under NDC 69238153205. Its NADAC has been published 328 times since Jun 24, 2020.
FDA first approved this application on Dec 26, 2018. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Amneal Pharmaceuticals NY LLCNDC
69238153205
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA211256FDA Approved
12/26/2018
TE Code
AB1
On Market Since
12/28/2018
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% CREAM has been published 328 times since Jun 24, 2020, and over the history we have for it it has declined 77.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1930 per GM |
|---|---|
| All-time high | $0.8624 (Jul 15, 2020) |
| All-time low | $0.1431 (Jul 17, 2024) |
| 52-week high | $0.1930 |
| 52-week low | $0.1787 |
| Median price | $0.2279 |
| Average price | $0.3677 |
| Largest weekly change | +47.8% (Aug 21, 2024) |
| Weeks tracked | 328 |
| Tracking since | Jun 24, 2020 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 40% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Amneal Pharmaceuticals NY LLC manufacturer profile
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Drug market
Clobetasol Propionate market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% CREAM, manufactured by Amneal Pharmaceuticals NY LLC, is $0.1930 per GM (NDC 69238153205), effective Sep 30, 2026.
How has the price of CLOBETASOL 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% CREAM has declined 77.6%. It has been tracked across 328 weekly CMS publications since Jun 24, 2020.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% CREAM?
Since Jun 24, 2020, the NADAC for CLOBETASOL 0.05% CREAM has ranged from a low of $0.1431 (Jul 17, 2024) to a high of $0.8624 (Jul 15, 2020), with a median of $0.2279 per GM.
Are there cheaper alternatives to CLOBETASOL 0.05% CREAM?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% CREAM, is $0.1152 per GM — about 40% below CLOBETASOL 0.05% CREAM.
Who manufactures CLOBETASOL 0.05% CREAM?
CLOBETASOL 0.05% CREAM (NDC 69238153205) is labeled by Amneal Pharmaceuticals NY LLC, and CMS classifies it as a generic product.