Product Information

CLOBETASOL 0.05% CREAM is a generic product labeled by Amneal Pharmaceuticals NY LLC, priced at $0.1884 per GM under NDC 69238153205. Its NADAC has been published 322 times since Jun 24, 2020.

FDA first approved this application on Dec 26, 2018. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CLOBETASOL 0.05% CREAM

Clobetasol Propionate
$0.1884per GM

Strength

.5 mg/g

NDC

69238153205

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

CLOBETASOL PROPIONATE

Approval Type

Generic (ANDA)

FDA Application

ANDA211256

FDA Approved

12/26/2018

TE Code

AB1

On Market Since

12/28/2018

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for CLOBETASOL 0.05% CREAM has been published 322 times since Jun 24, 2020, and over the history we have for it it has declined 78.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1884 per GM
All-time high$0.8624 (Jul 15, 2020)
All-time low$0.1431 (Jul 17, 2024)
52-week high$0.1884
52-week low$0.1787
Median price$0.2300
Average price$0.3710
Largest weekly change+47.8% (Aug 21, 2024)
Weeks tracked322
Tracking sinceJun 24, 2020

Price History

1W

+2.4%

1M

+2.4%

3M

+3.3%

6M

+2.3%

1Y

+2.2%

3Y

-28.7%

5Y

-74.0%

All

-78.2%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 39% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CLOBETASOL 0.05% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% CREAM, manufactured by Amneal Pharmaceuticals NY LLC, is $0.1884 per GM (NDC 69238153205), effective Aug 19, 2026.

How has the price of CLOBETASOL 0.05% CREAM changed over time?

Over the history we have for it, the NADAC for CLOBETASOL 0.05% CREAM has declined 78.2%. It has been tracked across 322 weekly CMS publications since Jun 24, 2020.

What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% CREAM?

Since Jun 24, 2020, the NADAC for CLOBETASOL 0.05% CREAM has ranged from a low of $0.1431 (Jul 17, 2024) to a high of $0.8624 (Jul 15, 2020), with a median of $0.2300 per GM.

Are there cheaper alternatives to CLOBETASOL 0.05% CREAM?

Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% CREAM, is $0.1152 per GM — about 39% below CLOBETASOL 0.05% CREAM.

Who manufactures CLOBETASOL 0.05% CREAM?

CLOBETASOL 0.05% CREAM (NDC 69238153205) is labeled by Amneal Pharmaceuticals NY LLC, and CMS classifies it as a generic product.