Product Information
CLOBETASOL 0.05% CREAM is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.1216 per GM under NDC 68180095603. Its NADAC has been published 417 times since Oct 10, 2018.
FDA first approved this application on Jan 30, 2018. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Lupin Pharmaceuticals Inc.NDC
68180095603
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA210208FDA Approved
1/30/2018
TE Code
AB1
On Market Since
8/17/2018
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% CREAM has been published 417 times since Oct 10, 2018, and over the history we have for it it has declined 90.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1216 per GM |
|---|---|
| All-time high | $1.3013 (Oct 10, 2018) |
| All-time low | $0.0808 (Nov 20, 2024) |
| 52-week high | $0.1487 |
| 52-week low | $0.1096 |
| Median price | $0.2472 |
| Average price | $0.4238 |
| Largest weekly change | +45.4% (Aug 21, 2024) |
| Weeks tracked | 417 |
| Tracking since | Oct 10, 2018 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 5% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Lupin Pharmaceuticals Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Clobetasol Propionate market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% CREAM, manufactured by Lupin Pharmaceuticals Inc., is $0.1216 per GM (NDC 68180095603), effective Sep 30, 2026.
How has the price of CLOBETASOL 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% CREAM has declined 90.7%. It has been tracked across 417 weekly CMS publications since Oct 10, 2018.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% CREAM?
Since Oct 10, 2018, the NADAC for CLOBETASOL 0.05% CREAM has ranged from a low of $0.0808 (Nov 20, 2024) to a high of $1.3013 (Oct 10, 2018), with a median of $0.2472 per GM.
Are there cheaper alternatives to CLOBETASOL 0.05% CREAM?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% CREAM, is $0.1152 per GM — about 5% below CLOBETASOL 0.05% CREAM.
Who manufactures CLOBETASOL 0.05% CREAM?
CLOBETASOL 0.05% CREAM (NDC 68180095603) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.