Product Information

ALLERGY RELIEF 25 MG SOFTGEL is a generic product labeled by Cardinal Health, priced at $0.0542 per EA under NDC 70000058501. Its NADAC has been published 217 times since Jun 29, 2022.

ALLERGY RELIEF 25 MG SOFTGEL

Diphenhydramine Hydrochloride
$0.0542per EA
OTC

Strength

25 mg/1

Manufacturer

Cardinal Health

NDC

70000058501

Classification

Generic

Dosage Form

CAPSULE, LIQUID FILLED

Route

ORAL

Effective Date

8/19/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

9/15/2021

Pharmacological Classes

Histamine H1 Receptor Antagonists
Histamine-1 Receptor Antagonist

Price Statistics

The NADAC for ALLERGY RELIEF 25 MG SOFTGEL has been published 217 times since Jun 29, 2022, and over the history we have for it it has risen 65.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0542 per EA
All-time high$0.0640 (Feb 11, 2026)
All-time low$0.0303 (Dec 21, 2022)
52-week high$0.0640
52-week low$0.0483
Median price$0.0419
Average price$0.0448
Largest weekly change+27.5% (Jan 18, 2023)
Weeks tracked217
Tracking sinceJun 29, 2022

Price History

1W

-2.8%

1M

-2.8%

3M

-10.3%

6M

-12.4%

1Y

+12.1%

3Y

+29.7%

5Y

N/A

All

+65.7%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 23% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ALLERGY RELIEF 25 MG SOFTGEL?

The current National Average Drug Acquisition Cost (NADAC) for ALLERGY RELIEF 25 MG SOFTGEL, manufactured by Cardinal Health, is $0.0542 per EA (NDC 70000058501), effective Aug 19, 2026.

How has the price of ALLERGY RELIEF 25 MG SOFTGEL changed over time?

Over the history we have for it, the NADAC for ALLERGY RELIEF 25 MG SOFTGEL has risen 65.7%. It has been tracked across 217 weekly CMS publications since Jun 29, 2022.

What are the highest and lowest recorded NADAC prices for ALLERGY RELIEF 25 MG SOFTGEL?

Since Jun 29, 2022, the NADAC for ALLERGY RELIEF 25 MG SOFTGEL has ranged from a low of $0.0303 (Dec 21, 2022) to a high of $0.0640 (Feb 11, 2026), with a median of $0.0419 per EA.

Are there cheaper alternatives to ALLERGY RELIEF 25 MG SOFTGEL?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DIPHENHYDRAMINE 25 MG CAPSULE, is $0.0415 per EA — about 23% below ALLERGY RELIEF 25 MG SOFTGEL.

Who manufactures ALLERGY RELIEF 25 MG SOFTGEL?

ALLERGY RELIEF 25 MG SOFTGEL (NDC 70000058501) is labeled by Cardinal Health, and CMS classifies it as a generic product.