This NDC is on FDA's drug shortage list (posted Dec 15, 2021)
Product Information
METHYLPREDNISOLONE 80 MG/ML VL is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $11.9243 per ML under NDC 70121157401. Its NADAC has been published 146 times since May 18, 2022.
FDA first approved this application on May 20, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Methylprednisolone acetate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
80 mg/mL
Manufacturer
Amneal Pharmaceuticals LLCNDC
70121157401
Classification
Generic
Dosage Form
INJECTION, SUSPENSION
Route
INTRA-ARTICULAR; INTRALESIONAL; INTRAMUSCULAR; SOFT TISSUE
Effective Date
7/22/2026
Active Ingredients
METHYLPREDNISOLONE ACETATEApproval Type
Generic (ANDA)
FDA Application
ANDA210043FDA Approved
5/20/2019
TE Code
AB
On Market Since
5/20/2019
Pharmacological Classes
Price Statistics
The NADAC for METHYLPREDNISOLONE 80 MG/ML VL has been published 146 times since May 18, 2022, and over the history we have for it it has declined 10.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $11.9243 per ML |
|---|---|
| All-time high | $13.3014 (May 10, 2023) |
| All-time low | $11.4040 (Dec 18, 2024) |
| 52-week high | $12.2840 |
| 52-week low | $11.4040 |
| Median price | $12.0835 |
| Average price | $12.2751 |
| Largest weekly change | -14.3% (Dec 18, 2024) |
| Weeks tracked | 146 |
| Tracking since | May 18, 2022 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Amneal Pharmaceuticals LLC manufacturer profile
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Drug market
Methylprednisolone acetate market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METHYLPREDNISOLONE 80 MG/ML VL?
The current National Average Drug Acquisition Cost (NADAC) for METHYLPREDNISOLONE 80 MG/ML VL, manufactured by Amneal Pharmaceuticals LLC, is $11.9243 per ML (NDC 70121157401), effective Sep 30, 2026.
How has the price of METHYLPREDNISOLONE 80 MG/ML VL changed over time?
Over the history we have for it, the NADAC for METHYLPREDNISOLONE 80 MG/ML VL has declined 10.4%. It has been tracked across 146 weekly CMS publications since May 18, 2022.
What are the highest and lowest recorded NADAC prices for METHYLPREDNISOLONE 80 MG/ML VL?
Since May 18, 2022, the NADAC for METHYLPREDNISOLONE 80 MG/ML VL has ranged from a low of $11.4040 (Dec 18, 2024) to a high of $13.3014 (May 10, 2023), with a median of $12.0835 per ML.
Are there cheaper alternatives to METHYLPREDNISOLONE 80 MG/ML VL?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METHYLPREDNISOLONE 80 MG/ML VL in a comparable dosage form, but none are currently priced below it.
Who manufactures METHYLPREDNISOLONE 80 MG/ML VL?
METHYLPREDNISOLONE 80 MG/ML VL (NDC 70121157401) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.
Is METHYLPREDNISOLONE 80 MG/ML VL in shortage?
Yes — NDC 70121157401 is currently listed in FDA's drug shortage database (posted Dec 15, 2021).