Product Information

METHYLPREDNISOLONE 400 MG/5 ML is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $13.0533 per ML under NDC 70121161001. Its NADAC has been published 87 times since Sep 18, 2024.

METHYLPREDNISOLONE 400 MG/5 ML

Methylprednisolone acetate
$13.0533per ML

Strength

80 mg/mL

NDC

70121161001

Classification

Generic

Dosage Form

INJECTION, SUSPENSION

Route

INTRA-ARTICULAR; INTRALESIONAL; INTRAMUSCULAR; INTRASYNOVIAL; SOFT TISSUE

Last Updated

5/21/2025

Active Ingredients

METHYLPREDNISOLONE ACETATE

Approval Type

Generic (ANDA)

FDA Application

ANDA216502

On Market Since

11/10/2023

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for METHYLPREDNISOLONE 400 MG/5 ML has been published 87 times since Sep 18, 2024, and over the history we have for it it has declined 12.8%. The table below summarizes its recorded NADAC range and movement.

Current price$13.0533 per ML
All-time high$14.9732 (Oct 16, 2024)
All-time low$13.0533 (May 21, 2025)
52-week high$13.0533
52-week low$13.0533
Median price$13.0533
Average price$13.4333
Largest weekly change-5.1% (Oct 23, 2024)
Weeks tracked87
Tracking sinceSep 18, 2024

Price History

1W

0.0%

1M

0.0%

3M

0.0%

6M

0.0%

1Y

0.0%

3Y

N/A

5Y

N/A

All

-12.8%

Generic Alternatives

The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 10% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METHYLPREDNISOLONE 400 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for METHYLPREDNISOLONE 400 MG/5 ML, manufactured by Amneal Pharmaceuticals LLC, is $13.0533 per ML (NDC 70121161001), effective May 13, 2026.

How has the price of METHYLPREDNISOLONE 400 MG/5 ML changed over time?

Over the history we have for it, the NADAC for METHYLPREDNISOLONE 400 MG/5 ML has declined 12.8%. It has been tracked across 87 weekly CMS publications since Sep 18, 2024.

What are the highest and lowest recorded NADAC prices for METHYLPREDNISOLONE 400 MG/5 ML?

Since Sep 18, 2024, the NADAC for METHYLPREDNISOLONE 400 MG/5 ML has ranged from a low of $13.0533 (May 21, 2025) to a high of $14.9732 (Oct 16, 2024), with a median of $13.0533 per ML.

Are there cheaper alternatives to METHYLPREDNISOLONE 400 MG/5 ML?

Yes. 2 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, METHYLPREDNISOLONE 80 MG/ML VL, is $11.8034 per ML — about 10% below METHYLPREDNISOLONE 400 MG/5 ML.

Who manufactures METHYLPREDNISOLONE 400 MG/5 ML?

METHYLPREDNISOLONE 400 MG/5 ML (NDC 70121161001) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.