Product Information
MEMANTINE HCL ER 21 MG CAPSULE is a generic product labeled by Slate Run Pharmaceuticals LLC, priced at $0.3563 per EA under NDC 70436005604. Its NADAC has been published 243 times since Feb 9, 2022.
FDA first approved this application on Apr 2, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
21 mg/1
Manufacturer
Slate Run Pharmaceuticals LLCNDC
70436005604
Classification
Generic
Dosage Form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
MEMANTINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA211100FDA Approved
4/2/2021
TE Code
AB
On Market Since
11/15/2021
Pharmacological Classes
Price Statistics
The NADAC for MEMANTINE HCL ER 21 MG CAPSULE has been published 243 times since Feb 9, 2022, and over the history we have for it it has declined 65.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3563 per EA |
|---|---|
| All-time high | $1.4635 (Mar 16, 2022) |
| All-time low | $0.3021 (Dec 17, 2025) |
| 52-week high | $0.3820 |
| 52-week low | $0.3021 |
| Median price | $0.4738 |
| Average price | $0.5669 |
| Largest weekly change | +71.8% (Oct 19, 2022) |
| Weeks tracked | 243 |
| Tracking since | Feb 9, 2022 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Slate Run Pharmaceuticals LLC manufacturer profile
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Drug market
memantine hydrochloride market comparison
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Therapeutic class
N-methyl-D-aspartate Receptor Antagonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of MEMANTINE HCL ER 21 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for MEMANTINE HCL ER 21 MG CAPSULE, manufactured by Slate Run Pharmaceuticals LLC, is $0.3563 per EA (NDC 70436005604), effective Sep 30, 2026.
How has the price of MEMANTINE HCL ER 21 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for MEMANTINE HCL ER 21 MG CAPSULE has declined 65.4%. It has been tracked across 243 weekly CMS publications since Feb 9, 2022.
What are the highest and lowest recorded NADAC prices for MEMANTINE HCL ER 21 MG CAPSULE?
Since Feb 9, 2022, the NADAC for MEMANTINE HCL ER 21 MG CAPSULE has ranged from a low of $0.3021 (Dec 17, 2025) to a high of $1.4635 (Mar 16, 2022), with a median of $0.4738 per EA.
Are there cheaper alternatives to MEMANTINE HCL ER 21 MG CAPSULE?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as MEMANTINE HCL ER 21 MG CAPSULE in a comparable dosage form, but none are currently priced below it.
Who manufactures MEMANTINE HCL ER 21 MG CAPSULE?
MEMANTINE HCL ER 21 MG CAPSULE (NDC 70436005604) is labeled by Slate Run Pharmaceuticals LLC, and CMS classifies it as a generic product.