Product Information

CLOBETASOL 0.05% CREAM is a generic product labeled by Xiromed LLC, priced at $0.1884 per GM under NDC 70700010915. Its NADAC has been published 402 times since Dec 12, 2018.

FDA first approved this application on Jun 15, 2018. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CLOBETASOL 0.05% CREAM

Clobetasol Propionate
$0.1884per GM

Strength

.5 mg/g

Manufacturer

Xiromed LLC

NDC

70700010915

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

CLOBETASOL PROPIONATE

Approval Type

Generic (ANDA)

FDA Application

ANDA210034

FDA Approved

6/15/2018

TE Code

AB1

On Market Since

6/19/2018

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for CLOBETASOL 0.05% CREAM has been published 402 times since Dec 12, 2018, and over the history we have for it it has declined 81.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1884 per GM
All-time high$1.0878 (Jan 16, 2019)
All-time low$0.1431 (Jul 17, 2024)
52-week high$0.1884
52-week low$0.1787
Median price$0.3129
Average price$0.4838
Largest weekly change+47.8% (Aug 21, 2024)
Weeks tracked402
Tracking sinceDec 12, 2018

Price History

1W

+2.4%

1M

+2.4%

3M

+3.3%

6M

+2.3%

1Y

+2.2%

3Y

-28.7%

5Y

-74.0%

All

-81.4%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 39% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CLOBETASOL 0.05% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% CREAM, manufactured by Xiromed LLC, is $0.1884 per GM (NDC 70700010915), effective Aug 19, 2026.

How has the price of CLOBETASOL 0.05% CREAM changed over time?

Over the history we have for it, the NADAC for CLOBETASOL 0.05% CREAM has declined 81.4%. It has been tracked across 402 weekly CMS publications since Dec 12, 2018.

What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% CREAM?

Since Dec 12, 2018, the NADAC for CLOBETASOL 0.05% CREAM has ranged from a low of $0.1431 (Jul 17, 2024) to a high of $1.0878 (Jan 16, 2019), with a median of $0.3129 per GM.

Are there cheaper alternatives to CLOBETASOL 0.05% CREAM?

Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% CREAM, is $0.1152 per GM — about 39% below CLOBETASOL 0.05% CREAM.

Who manufactures CLOBETASOL 0.05% CREAM?

CLOBETASOL 0.05% CREAM (NDC 70700010915) is labeled by Xiromed LLC, and CMS classifies it as a generic product.