Product Information
LOTEPREDNOL ETABONATE 0.5% DRP is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $10.5316 per ML under NDC 70748030001. Its NADAC has been published 50 times since Sep 10, 2025.
FDA first approved this application on Apr 24, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/mL
Manufacturer
Lupin Pharmaceuticals Inc.NDC
70748030001
Classification
Generic
Dosage Form
SUSPENSION
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
LOTEPREDNOL ETABONATEApproval Type
Generic (ANDA)
FDA Application
ANDA215719FDA Approved
4/24/2024
TE Code
AB
On Market Since
7/1/2025
Pharmacological Classes
Price Statistics
The NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has been published 50 times since Sep 10, 2025, and over the history we have for it it has declined 48.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $10.5316 per ML |
|---|---|
| All-time high | $20.4008 (Sep 10, 2025) |
| All-time low | $10.1799 (Jul 22, 2026) |
| 52-week high | $20.4008 |
| 52-week low | $10.1799 |
| Median price | $14.0459 |
| Average price | $15.1249 |
| Largest weekly change | -19.6% (Feb 18, 2026) |
| Weeks tracked | 50 |
| Tracking since | Sep 10, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LOTEPREDNOL ETABONATE 0.5% DRP?
The current National Average Drug Acquisition Cost (NADAC) for LOTEPREDNOL ETABONATE 0.5% DRP, manufactured by Lupin Pharmaceuticals Inc., is $10.5316 per ML (NDC 70748030001), effective Aug 19, 2026.
How has the price of LOTEPREDNOL ETABONATE 0.5% DRP changed over time?
Over the history we have for it, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has declined 48.4%. It has been tracked across 50 weekly CMS publications since Sep 10, 2025.
What are the highest and lowest recorded NADAC prices for LOTEPREDNOL ETABONATE 0.5% DRP?
Since Sep 10, 2025, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has ranged from a low of $10.1799 (Jul 22, 2026) to a high of $20.4008 (Sep 10, 2025), with a median of $14.0459 per ML.
Are there cheaper alternatives to LOTEPREDNOL ETABONATE 0.5% DRP?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LOTEPREDNOL ETABONATE 0.5% DRP in a comparable dosage form, but none are currently priced below it.
Who manufactures LOTEPREDNOL ETABONATE 0.5% DRP?
LOTEPREDNOL ETABONATE 0.5% DRP (NDC 70748030001) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.