Drug Markets/Loteprednol Etabonate

Loteprednol Etabonate

35 NDCs across 10 manufacturers|25 Generic,10 Brand

Loteprednol Etabonate is used to treat allergic conjunctivitis, bacterial conjunctivitis, viral conjunctivitis, edema, inflammation and iritis, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved on Mar 9, 1998, and the first generic was approved Apr 17, 2019. FDA's Orange Book lists 16 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $79 million on Loteprednol Etabonate across 339,000 claims for 187,000 beneficiaries.

Loteprednol Etabonate is available as 35 NDCs from 10 manufacturers (25 generic, 10 brand), with NADAC prices from $10.53 to $103.18 per ML — the most expensive product costs about 9.8× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

25G / 10B

Manufacturers

competing in market

Price Spread

$10.53 – $103.18

per ML, 29 of 35 NDCs

7d Activity

15↑13↓7 flat

avg +1.6% WoW · of 35 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Manufacturer Breakdown

10 manufacturers producing LOTEPREDNOL ETABONATE(2 pricing outliers)

Bausch & Lomb Incorporated

Bausch & Lomb Americas Inc.

5 NDCs

$19.6565

avg/unit

ARMAS PHARMACEUTICALS INC.

Sun Pharmaceutical Industries Inc.

Oceanside Pharmaceuticals

3 NDCs

$19.2081

avg/unit

Alcon Laboratories, Inc.

Amneal Pharmaceuticals NY LLC

2 NDCs

$21.4156

avg/unit

Lupin Pharmaceuticals Inc.

2 NDCs

$16.1751

avg/unit

Drug Portfolio

35 NDCs total, 35 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
INVELTYS 1% EYE DROP	71571012128	Alcon Laboratories, Inc.	$103.1847 per ML	High Outlier	Brand	-0.04%	Corticosteroid
LOTEMAX 0.5% EYE OINTMENT	24208044335	Bausch & Lomb Incorporated	$99.7902 per GM	High Outlier	Brand	-0.01%	Corticosteroid
LOTEMAX 0.5% EYE DROPS	24208029905	Bausch & Lomb Incorporated	$61.9764 per ML	High Outlier	Brand	—	Corticosteroid
LOTEMAX 0.5% EYE DROPS	24208029910	Bausch & Lomb Incorporated	$61.7671 per ML	High Outlier	Brand	—	Corticosteroid
EYSUVIS 0.25% EYE DROPS	71571033383	Alcon Laboratories, Inc.	$61.5456 per ML	High Outlier	Brand	-0.01%	Corticosteroid
ALREX 0.2% EYE DROPS	24208035305	Bausch & Lomb Incorporated	$58.0305 per ML	High Outlier	Brand	-0.01%	Corticosteroid
ALREX 0.2% EYE DROPS	24208035310	Bausch & Lomb Incorporated	$58.0100 per ML	High Outlier	Brand	—	Corticosteroid
LOTEMAX 0.5% OPHTHALMIC GEL	24208050307	Bausch & Lomb Incorporated	$49.6190 per GM	High Outlier	Brand	+0.09%	Corticosteroid
LOTEMAX SM 0.38% OPHTH GEL	24208050707	Bausch & Lomb Incorporated	$49.4864 per GM	High Outlier	Brand	+0.01%	Corticosteroid
LOTEMAX 0.5% EYE DROPS	24208029915	Bausch & Lomb Incorporated	$36.7339 per ML	High Outlier	Brand	—	Corticosteroid
LOTEPREDNOL ETABONATE 0.2% DRP	60219136603	Amneal Pharmaceuticals NY LLC	$32.2996 per ML	—	Generic	+1.02%	Corticosteroid
LOTEPREDNOL ETABONATE 0.2% DRP	72485065305	ARMAS PHARMACEUTICALS INC.	$32.2996 per ML	—	Generic	+1.02%	Corticosteroid
LOTEPREDNOL ETABONATE 0.2% DRP	82260036105	Bausch & Lomb Americas Inc.	$32.2996 per ML	—	Generic	+1.02%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	82260029910	Bausch & Lomb Americas Inc.	$21.8186 per ML	—	Generic	-0.89%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	00574413510	Padagis US LLC	$21.8186 per ML	—	Generic	-0.89%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	62756023255	Sun Pharmaceutical Industries Inc.	$21.8186 per ML	—	Generic	-0.89%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	70748030002	Lupin Pharmaceuticals Inc.	$21.8186 per ML	—	Generic	-0.89%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	72603032402	NorthStar Rx LLC	$21.8186 per ML	—	Generic	-0.89%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	68682029910	Oceanside Pharmaceuticals	$20.2655 per ML	—	Generic	—	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	68682029905	Oceanside Pharmaceuticals	$19.5173 per ML	—	Generic	—	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	68682029915	Oceanside Pharmaceuticals	$17.8414 per ML	—	Generic	—	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	62756023256	Sun Pharmaceutical Industries Inc.	$17.5474 per ML	—	Generic	-2.20%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	82260029915	Bausch & Lomb Americas Inc.	$17.5474 per ML	—	Generic	-2.20%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	00574413515	Padagis US LLC	$17.5474 per ML	—	Generic	-2.20%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	72603032403	NorthStar Rx LLC	$17.5474 per ML	—	Generic	-2.20%	Corticosteroid
LOTEPREDNOL 0.5% OPHTHALMC GEL	72485063005	ARMAS PHARMACEUTICALS INC.	$16.0854 per GM	—	Generic	+10.47%	Corticosteroid
LOTEPREDNOL 0.5% OPHTHALMC GEL	24208050801	Bausch & Lomb Incorporated	$16.0854 per GM	High Outlier	Generic	+10.47%	Corticosteroid
LOTEPREDNOL 0.5% OPHTHALMC GEL	82260050801	Bausch & Lomb Americas Inc.	$16.0854 per GM	—	Generic	+10.47%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	82260029905	Bausch & Lomb Americas Inc.	$10.5316 per ML	—	Generic	+3.45%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	72603032401	NorthStar Rx LLC	$10.5316 per ML	—	Generic	+3.45%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	72485066505	ARMAS PHARMACEUTICALS INC.	$10.5316 per ML	—	Generic	+3.45%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	00574413505	Padagis US LLC	$10.5316 per ML	—	Generic	+3.45%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	70748030001	Lupin Pharmaceuticals Inc.	$10.5316 per ML	—	Generic	+3.45%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	62756023290	Sun Pharmaceutical Industries Inc.	$10.5316 per ML	—	Generic	+3.45%	Corticosteroid
LOTEPREDNOL ETABONATE 0.5% DRP	60219136201	Amneal Pharmaceuticals NY LLC	$10.5316 per ML	—	Generic	+3.45%	Corticosteroid

Frequently Asked Questions

What is Loteprednol Etabonate used to treat?

When did Loteprednol Etabonate become available as a generic?

FDA approved the first generic Loteprednol Etabonate (ANDA) on Apr 17, 2019. The Orange Book currently lists 16 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How much does Medicare spend on Loteprednol Etabonate?

In 2024, Medicare Part D spent $79 million on Loteprednol Etabonate across 339,000 claims for 187,000 beneficiaries.

How many Loteprednol Etabonate products are on the market?

The Loteprednol Etabonate drug market contains 35 NDCs from 10 manufacturers — 25 generic and 10 brand products.

What is the price range for Loteprednol Etabonate?

NADAC reference prices for Loteprednol Etabonate range from $10.5316 to $103.1847 per ML — the most expensive product costs about 9.8× the cheapest. 6 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.

Is generic Loteprednol Etabonate cheaper than brand?

The average generic NADAC for Loteprednol Etabonate is $18.5239 per ML, versus $63.0355 for brand-labeled products — brand versions average about 3.4× the generic price.

Which manufacturers make Loteprednol Etabonate?

10 manufacturers list Loteprednol Etabonate in NADAC. Ranked by number of NDCs, the largest are Bausch & Lomb Incorporated (9), Bausch & Lomb Americas Inc. (5), ARMAS PHARMACEUTICALS INC. (3), Padagis US LLC (3), Sun Pharmaceutical Industries Inc. (3).

How has the price of Loteprednol Etabonate changed recently?

Over the past 7 days, 15 Loteprednol Etabonate NDCs rose and 13 fell, with a market-wide average change of +1.6%.