Product Information
BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB is a generic product labeled by ANI Pharmaceuticals, Inc., priced at $0.2138 per EA under NDC 70954041240. Its NADAC has been published 131 times since Feb 22, 2023.
FDA first approved this application on Nov 4, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Bisoprolol Fumarate and Hydrochlorothiazide market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB
Bisoprolol Fumarate and HydrochlorothiazideStrength
2.5; 6.25 mg/1; mg/1
Manufacturer
ANI Pharmaceuticals, Inc.NDC
70954041240
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/20/2025
Active Ingredients
BISOPROLOL FUMARATE; HYDROCHLOROTHIAZIDEApproval Type
Generic (ANDA)
FDA Application
ANDA215562FDA Approved
11/4/2021
TE Code
AB
On Market Since
11/4/2021
Pharmacological Classes
Price Statistics
The NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB has been published 131 times since Feb 22, 2023, and over the history we have for it it has declined 21.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2138 per EA |
|---|---|
| All-time high | $0.3349 (Dec 13, 2023) |
| All-time low | $0.1729 (Nov 20, 2024) |
| Median price | $0.2370 |
| Average price | $0.2403 |
| Largest weekly change | +63.0% (Nov 22, 2023) |
| Weeks tracked | 131 |
| Tracking since | Feb 22, 2023 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
-4.4%
5Y
N/A
All
-21.5%
Last surveyed Aug 20, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 0% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
ANI Pharmaceuticals, Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Bisoprolol Fumarate and Hydrochlorothiazide market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Thiazide Diuretic class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB?
The current National Average Drug Acquisition Cost (NADAC) for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB, manufactured by ANI Pharmaceuticals, Inc., is $0.2138 per EA (NDC 70954041240), effective Aug 20, 2025.
How has the price of BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB changed over time?
Over the history we have for it, the NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB has declined 21.5%. It has been tracked across 131 weekly CMS publications since Feb 22, 2023.
What are the highest and lowest recorded NADAC prices for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB?
Since Feb 22, 2023, the NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB has ranged from a low of $0.1729 (Nov 20, 2024) to a high of $0.3349 (Dec 13, 2023), with a median of $0.2370 per EA.
Are there cheaper alternatives to BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB, is $0.2133 per EA — about 0% below BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB.
Who manufactures BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB?
BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB (NDC 70954041240) is labeled by ANI Pharmaceuticals, Inc., and CMS classifies it as a generic product.