Product Information
ESTRADIOL 0.06% 1.25G GEL PUMP is a generic product labeled by ANI Pharmaceuticals, Inc., priced at $3.4144 per GM under NDC 70954064610. Its NADAC has been published 91 times since Nov 27, 2024.
FDA first approved this application on Oct 23, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.75 mg/1.25g
Manufacturer
ANI Pharmaceuticals, Inc.NDC
70954064610
Classification
Generic
Dosage Form
GEL, METERED
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA217882FDA Approved
10/23/2024
TE Code
AB
On Market Since
10/23/2024
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.06% 1.25G GEL PUMP has been published 91 times since Nov 27, 2024, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.4144 per GM |
|---|---|
| All-time high | $3.5615 (Apr 15, 2026) |
| All-time low | $3.4144 (Mar 19, 2025) |
| 52-week high | $3.5615 |
| 52-week low | $3.4144 |
| Median price | $3.4815 |
| Average price | $3.4867 |
| Largest weekly change | -2.6% (Aug 19, 2026) |
| Weeks tracked | 91 |
| Tracking since | Nov 27, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.06% 1.25G GEL PUMP?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.06% 1.25G GEL PUMP, manufactured by ANI Pharmaceuticals, Inc., is $3.4144 per GM (NDC 70954064610), effective Aug 19, 2026.
How has the price of ESTRADIOL 0.06% 1.25G GEL PUMP changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.06% 1.25G GEL PUMP has held within roughly two percent of its current level. It has been tracked across 91 weekly CMS publications since Nov 27, 2024.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.06% 1.25G GEL PUMP?
Since Nov 27, 2024, the NADAC for ESTRADIOL 0.06% 1.25G GEL PUMP has ranged from a low of $3.4144 (Mar 19, 2025) to a high of $3.5615 (Apr 15, 2026), with a median of $3.4815 per GM.
Are there cheaper alternatives to ESTRADIOL 0.06% 1.25G GEL PUMP?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as ESTRADIOL 0.06% 1.25G GEL PUMP in a comparable dosage form, but none are currently priced below it.
Who manufactures ESTRADIOL 0.06% 1.25G GEL PUMP?
ESTRADIOL 0.06% 1.25G GEL PUMP (NDC 70954064610) is labeled by ANI Pharmaceuticals, Inc., and CMS classifies it as a generic product.