Product Information
BRIMONIDINE-TIMOLOL 0.2%-0.5% is a generic product labeled by Florida Pharmaceutical Products, LLC, priced at $2.4609 per ML under NDC 71921018810. Its NADAC has been published 137 times since Jan 10, 2024.
FDA first approved this application on Oct 4, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2; 5 mg/mL; mg/mL
Manufacturer
Florida Pharmaceutical Products, LLCNDC
71921018810
Classification
Generic
Dosage Form
SOLUTION
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
BRIMONIDINE TARTRATE; TIMOLOL MALEATEApproval Type
Generic (ANDA)
FDA Application
ANDA201949FDA Approved
10/4/2022
TE Code
AB
On Market Since
11/23/2023
Pharmacological Classes
Price Statistics
The NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has been published 137 times since Jan 10, 2024, and over the history we have for it it has declined 82.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.4609 per ML |
|---|---|
| All-time high | $16.7217 (Apr 10, 2024) |
| All-time low | $2.3704 (May 20, 2026) |
| 52-week high | $4.6326 |
| 52-week low | $2.3704 |
| Median price | $7.0952 |
| Average price | $7.2428 |
| Largest weekly change | +56.9% (May 22, 2024) |
| Weeks tracked | 137 |
| Tracking since | Jan 10, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 25% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BRIMONIDINE-TIMOLOL 0.2%-0.5%?
The current National Average Drug Acquisition Cost (NADAC) for BRIMONIDINE-TIMOLOL 0.2%-0.5%, manufactured by Florida Pharmaceutical Products, LLC, is $2.4609 per ML (NDC 71921018810), effective Aug 19, 2026.
How has the price of BRIMONIDINE-TIMOLOL 0.2%-0.5% changed over time?
Over the history we have for it, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has declined 82.7%. It has been tracked across 137 weekly CMS publications since Jan 10, 2024.
What are the highest and lowest recorded NADAC prices for BRIMONIDINE-TIMOLOL 0.2%-0.5%?
Since Jan 10, 2024, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has ranged from a low of $2.3704 (May 20, 2026) to a high of $16.7217 (Apr 10, 2024), with a median of $7.0952 per ML.
Are there cheaper alternatives to BRIMONIDINE-TIMOLOL 0.2%-0.5%?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BRIMONIDINE-TIMOLOL 0.2%-0.5%, is $1.8390 per ML — about 25% below BRIMONIDINE-TIMOLOL 0.2%-0.5%.
Who manufactures BRIMONIDINE-TIMOLOL 0.2%-0.5%?
BRIMONIDINE-TIMOLOL 0.2%-0.5% (NDC 71921018810) is labeled by Florida Pharmaceutical Products, LLC, and CMS classifies it as a generic product.