Product Information
BRIMONIDINE-TIMOLOL 0.2%-0.5% is a generic product labeled by Florida Pharmaceutical Products, LLC, priced at $1.9717 per ML under NDC 71921018815. Its NADAC has been published 143 times since Jan 10, 2024.
FDA first approved this application on Oct 4, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2; 5 mg/mL; mg/mL
Manufacturer
Florida Pharmaceutical Products, LLCNDC
71921018815
Classification
Generic
Dosage Form
SOLUTION
Route
OPHTHALMIC
Effective Date
9/23/2026
Active Ingredients
BRIMONIDINE TARTRATE; TIMOLOL MALEATEApproval Type
Generic (ANDA)
FDA Application
ANDA201949FDA Approved
10/4/2022
TE Code
AB
On Market Since
11/23/2023
Pharmacological Classes
Price Statistics
The NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has been published 143 times since Jan 10, 2024, and over the history we have for it it has declined 88.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.9717 per ML |
|---|---|
| All-time high | $17.1668 (Jan 10, 2024) |
| All-time low | $1.8390 (Aug 19, 2026) |
| 52-week high | $6.8975 |
| 52-week low | $1.8390 |
| Median price | $6.8975 |
| Average price | $6.9949 |
| Largest weekly change | +75.9% (Aug 21, 2024) |
| Weeks tracked | 143 |
| Tracking since | Jan 10, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Florida Pharmaceutical Products, LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Brimonidine tartrate and Timolol maleate market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
alpha-Adrenergic Agonist class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BRIMONIDINE-TIMOLOL 0.2%-0.5%?
The current National Average Drug Acquisition Cost (NADAC) for BRIMONIDINE-TIMOLOL 0.2%-0.5%, manufactured by Florida Pharmaceutical Products, LLC, is $1.9717 per ML (NDC 71921018815), effective Sep 30, 2026.
How has the price of BRIMONIDINE-TIMOLOL 0.2%-0.5% changed over time?
Over the history we have for it, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has declined 88.5%. It has been tracked across 143 weekly CMS publications since Jan 10, 2024.
What are the highest and lowest recorded NADAC prices for BRIMONIDINE-TIMOLOL 0.2%-0.5%?
Since Jan 10, 2024, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has ranged from a low of $1.8390 (Aug 19, 2026) to a high of $17.1668 (Jan 10, 2024), with a median of $6.8975 per ML.
Are there cheaper alternatives to BRIMONIDINE-TIMOLOL 0.2%-0.5%?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as BRIMONIDINE-TIMOLOL 0.2%-0.5% in a comparable dosage form, but none are currently priced below it.
Who manufactures BRIMONIDINE-TIMOLOL 0.2%-0.5%?
BRIMONIDINE-TIMOLOL 0.2%-0.5% (NDC 71921018815) is labeled by Florida Pharmaceutical Products, LLC, and CMS classifies it as a generic product.