Product Information

FENTANYL 250 MCG/5 ML VIAL is a generic product labeled by Civica, Inc., priced at $1.7269 per ML under NDC 72572017110. Its NADAC has been published 123 times since Apr 17, 2024.

FDA first approved this application on Jul 11, 1984. Its Orange Book therapeutic-equivalence code is AP.

FENTANYL 250 MCG/5 ML VIAL

Fentanyl Citrate
$1.7269per ML
DEA Schedule CII

Strength

50 ug/mL

Manufacturer

Civica, Inc.

NDC

72572017110

Classification

Generic

Dosage Form

INJECTION

Route

INTRAMUSCULAR; INTRAVENOUS

Effective Date

8/19/2026

Active Ingredients

FENTANYL CITRATE

Approval Type

New Drug (NDA)

FDA Application

NDA019101

FDA Approved

7/11/1984

TE Code

AP

On Market Since

12/10/2019

Pharmacological Classes

Full Opioid Agonists
Opioid Agonist

Price Statistics

The NADAC for FENTANYL 250 MCG/5 ML VIAL has been published 123 times since Apr 17, 2024, and over the history we have for it it has risen 147.2%. The table below summarizes its recorded NADAC range and movement.

Current price$1.7269 per ML
All-time high$1.7269 (Aug 19, 2026)
All-time low$0.6987 (Apr 17, 2024)
52-week high$1.7269
52-week low$0.8723
Median price$0.7707
Average price$0.9612
Largest weekly change+16.1% (Sep 17, 2025)
Weeks tracked123
Tracking sinceApr 17, 2024

Price History

1W

+9.1%

1M

+9.1%

3M

+33.3%

6M

+35.3%

1Y

+98.0%

3Y

N/A

5Y

N/A

All

+147.2%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 65% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of FENTANYL 250 MCG/5 ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for FENTANYL 250 MCG/5 ML VIAL, manufactured by Civica, Inc., is $1.7269 per ML (NDC 72572017110), effective Aug 19, 2026.

How has the price of FENTANYL 250 MCG/5 ML VIAL changed over time?

Over the history we have for it, the NADAC for FENTANYL 250 MCG/5 ML VIAL has risen 147.2%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.

What are the highest and lowest recorded NADAC prices for FENTANYL 250 MCG/5 ML VIAL?

Since Apr 17, 2024, the NADAC for FENTANYL 250 MCG/5 ML VIAL has ranged from a low of $0.6987 (Apr 17, 2024) to a high of $1.7269 (Aug 19, 2026), with a median of $0.7707 per ML.

Are there cheaper alternatives to FENTANYL 250 MCG/5 ML VIAL?

Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, FENTANYL 1,000 MCG/20 ML AMPUL, is $0.5981 per ML — about 65% below FENTANYL 250 MCG/5 ML VIAL.

Who manufactures FENTANYL 250 MCG/5 ML VIAL?

FENTANYL 250 MCG/5 ML VIAL (NDC 72572017110) is labeled by Civica, Inc., and CMS classifies it as a generic product.