Product Information

LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM is a generic product labeled by Viona Pharmaceuticals Inc., priced at $0.2211 per GM under NDC 72578016506. Its NADAC has been published 63 times since Jun 11, 2025.

FDA first approved this application on Dec 17, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM

Lidocaine and prilocaine
$0.2211per GM

Strength

25; 25 mg/g; mg/g

NDC

72578016506

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

LIDOCAINE; PRILOCAINE

Approval Type

Generic (ANDA)

FDA Application

ANDA219120

FDA Approved

12/17/2024

TE Code

AB

On Market Since

1/1/2025

Pharmacological Classes

Amide Local Anesthetic
Amide Local Anesthetic
Amides
Amides
Antiarrhythmic
Local Anesthesia
Local Anesthesia

Price Statistics

The NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has been published 63 times since Jun 11, 2025, and over the history we have for it it has declined 20.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2211 per GM
All-time high$0.2791 (Jun 11, 2025)
All-time low$0.2164 (Jun 17, 2026)
52-week high$0.2733
52-week low$0.2164
Median price$0.2694
Average price$0.2532
Largest weekly change-6.4% (Mar 18, 2026)
Weeks tracked63
Tracking sinceJun 11, 2025

Price History

1W

+1.3%

1M

+1.3%

3M

+1.2%

6M

-13.6%

1Y

-18.4%

3Y

N/A

5Y

N/A

All

-20.8%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Lidocaine and prilocaine market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM, manufactured by Viona Pharmaceuticals Inc., is $0.2211 per GM (NDC 72578016506), effective Aug 19, 2026.

How has the price of LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM changed over time?

Over the history we have for it, the NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has declined 20.8%. It has been tracked across 63 weekly CMS publications since Jun 11, 2025.

What are the highest and lowest recorded NADAC prices for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?

Since Jun 11, 2025, the NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has ranged from a low of $0.2164 (Jun 17, 2026) to a high of $0.2791 (Jun 11, 2025), with a median of $0.2694 per GM.

Are there cheaper alternatives to LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?

No other NADAC-published product currently shares the active ingredient and strength of LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?

LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM (NDC 72578016506) is labeled by Viona Pharmaceuticals Inc., and CMS classifies it as a generic product.