Product Information
LUBIPROSTONE 8 MCG CAPSULE is a generic product labeled by NorthStar Rx LLC, priced at $0.5493 per EA under NDC 72603028801. Its NADAC has been published 47 times since Oct 1, 2025.
FDA first approved this application on Jan 2, 2025. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.008 mg/1
Manufacturer
NorthStar Rx LLCNDC
72603028801
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
LUBIPROSTONEApproval Type
Generic (ANDA)
FDA Application
ANDA218640FDA Approved
1/2/2025
TE Code
AB
On Market Since
7/1/2025
Pharmacological Classes
Price Statistics
The NADAC for LUBIPROSTONE 8 MCG CAPSULE has been published 47 times since Oct 1, 2025, and over the history we have for it it has declined 27.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5493 per EA |
|---|---|
| All-time high | $0.7578 (Oct 15, 2025) |
| All-time low | $0.5493 (Aug 19, 2026) |
| 52-week high | $0.7578 |
| 52-week low | $0.5493 |
| Median price | $0.6936 |
| Average price | $0.6833 |
| Largest weekly change | -15.7% (Jun 17, 2026) |
| Weeks tracked | 47 |
| Tracking since | Oct 1, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LUBIPROSTONE 8 MCG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for LUBIPROSTONE 8 MCG CAPSULE, manufactured by NorthStar Rx LLC, is $0.5493 per EA (NDC 72603028801), effective Aug 19, 2026.
How has the price of LUBIPROSTONE 8 MCG CAPSULE changed over time?
Over the history we have for it, the NADAC for LUBIPROSTONE 8 MCG CAPSULE has declined 27.5%. It has been tracked across 47 weekly CMS publications since Oct 1, 2025.
What are the highest and lowest recorded NADAC prices for LUBIPROSTONE 8 MCG CAPSULE?
Since Oct 1, 2025, the NADAC for LUBIPROSTONE 8 MCG CAPSULE has ranged from a low of $0.5493 (Aug 19, 2026) to a high of $0.7578 (Oct 15, 2025), with a median of $0.6936 per EA.
Are there cheaper alternatives to LUBIPROSTONE 8 MCG CAPSULE?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LUBIPROSTONE 8 MCG CAPSULE in a comparable dosage form, but none are currently priced below it.
Who manufactures LUBIPROSTONE 8 MCG CAPSULE?
LUBIPROSTONE 8 MCG CAPSULE (NDC 72603028801) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.