Product Information

LUBIPROSTONE 24 MCG CAPSULE is a generic product labeled by Par Health USA, LLC, priced at $0.6239 per EA under NDC 00254302902. Its NADAC has been published 279 times since Apr 21, 2021.

FDA first approved this application on Jan 31, 2006. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

LUBIPROSTONE 24 MCG CAPSULE

Lubiprostone
$0.6239per EA

Strength

24 ug/1

NDC

00254302902

Classification

Generic

Dosage Form

CAPSULE, GELATIN COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

LUBIPROSTONE

Approval Type

Authorized Generic (NDA)

FDA Application

NDA021908

FDA Approved

1/31/2006

TE Code

AB

On Market Since

1/1/2021

Pharmacological Classes

Chloride Channel Activator
Chloride Channel Activators

Price Statistics

The NADAC for LUBIPROSTONE 24 MCG CAPSULE has been published 279 times since Apr 21, 2021, and over the history we have for it it has declined 86.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.6239 per EA
All-time high$4.7127 (May 12, 2021)
All-time low$0.5868 (Nov 20, 2024)
52-week high$0.8250
52-week low$0.6239
Median price$1.2408
Average price$2.2972
Largest weekly change+44.9% (Nov 22, 2023)
Weeks tracked279
Tracking sinceApr 21, 2021

Price History

1W

-1.0%

1M

-1.0%

3M

-6.0%

6M

-15.9%

1Y

-23.5%

3Y

-66.2%

5Y

-86.3%

All

-86.8%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LUBIPROSTONE 24 MCG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for LUBIPROSTONE 24 MCG CAPSULE, manufactured by Par Health USA, LLC, is $0.6239 per EA (NDC 00254302902), effective Aug 19, 2026.

How has the price of LUBIPROSTONE 24 MCG CAPSULE changed over time?

Over the history we have for it, the NADAC for LUBIPROSTONE 24 MCG CAPSULE has declined 86.8%. It has been tracked across 279 weekly CMS publications since Apr 21, 2021.

What are the highest and lowest recorded NADAC prices for LUBIPROSTONE 24 MCG CAPSULE?

Since Apr 21, 2021, the NADAC for LUBIPROSTONE 24 MCG CAPSULE has ranged from a low of $0.5868 (Nov 20, 2024) to a high of $4.7127 (May 12, 2021), with a median of $1.2408 per EA.

Are there cheaper alternatives to LUBIPROSTONE 24 MCG CAPSULE?

4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LUBIPROSTONE 24 MCG CAPSULE in a comparable dosage form, but none are currently priced below it.

Who manufactures LUBIPROSTONE 24 MCG CAPSULE?

LUBIPROSTONE 24 MCG CAPSULE (NDC 00254302902) is labeled by Par Health USA, LLC, and CMS classifies it as a generic product.